AgNOR计数对宫颈良恶性病变的鉴别诊断意义  

The Significance of AgNOR Count in the Differencial Diagnosis Between Benigh and Malignant Cervical Lesions

作　　者：胡伟 刘希光[2] 魏志敏[3] 

机构地区：[1]山东省青岛市骨伤医院妇产科,青岛市266021 [2]青岛大学医学院附属医院肿瘤科,青岛市266003 [3]青岛大学医学院附属医院病理科,青岛市266003

出　　处：《肿瘤防治杂志》2000年第4期381-382,共2页China Journal of Cancer Prevention and Treatment

摘　　要：目的 :探讨核仁形成区嗜银蛋白 (AgNOR)计数对宫颈良恶性病变鉴别诊断价值。方法 :采用AgNOR银染法对比 15例宫颈鳞癌与 2 2例慢性宫颈炎的AgNOR计数。结果 :宫颈鳞癌与宫颈良性病变的AgNOR计数差异有显著性 (P <0 0 1) ,宫颈不典型增生AgNOR计数也较宫颈良性增生上皮增高(P <0 0 5)。结论 :宫颈良恶性病变的AgNOR计数明显不同 ,此方法简便易行 ,可用于宫颈良恶性病变的鉴别。Objective:To study the value of AgNOR conut to the differencial diagnosis between benigh and malignant cervical lesions.Methods:The AgNOR count of cervical carcinoma in 15 cases was compared with that of chronic cervicitis in 22 cases by the silver staining method of AgNOR.Results:There was a significant difference of AgNOR count between the cervical squamous carcinoma and benigh lesions (P<001).Atypical hyperplasia of cervix had higher AgNOR count than benigh epithelial hyperplasia of cervix(P<005).Conclusons:There is a significant difference of AgNOR count between the cervical benigh and malignant lesions.The AgNOR count count is a simple and practical method and can be used as a way of pathologically differenciating between the cervical benigh and malignant lesions.

关 键 词：AGNOR 宫颈鳞癌 慢性宫颈炎 不典型增生 诊断 

分 类 号：R730.4[医药卫生—肿瘤]