合肥市全民食用碘盐前后儿童甲状腺功能研究  

A study of status of hypophysis thyroid function of children from Hefei city before and after universal salt iodizatton

作　　者：汪延华[1] 贾敬华[1] 潘天荣[1] 储小宏[1] 赵广碧[1] 孙家通 刘树琴[1] 包爱民[1] 章秋[1] 杨明功[1] 帅宗文[1] 徐胜前[1] 

机构地区：[1]安徽医科大学第一附属医院内分泌科,安徽合肥230022

出　　处：《中国地方病学杂志》2000年第5期324-326,共3页Chinese Jouranl of Endemiology

基　　金：卫生部全国地病办;安徽省地病办资助项目!(1995-04 )

摘　　要：目的　为获得全民食盐加碘前合肥市儿童垂体—甲状腺功能状态本底资料和食盐加碘后的影响情况。为城市碘盐的合理实施提供实验依据。方法　以 2 6 44 (前 )、2 395 (后 )名 7～ 14岁儿童为基础 ,以 8～ 10岁儿童为中心完成垂体—甲状腺功能多指标、多学科的综合对比研究。结果　发现食盐加碘前 TRH- ST6 0 min高于0 min3～ 4倍 ,FT3均值 5 .9pmol/ L、Tg均值 13.4μg/ L 均高于正常值上限。甲状腺吸碘率试验 (RIU)呈碘饥饿曲线。食盐加碘 1年后 TRH- ST曲线增高。其 6 0 m in>0 m in4.5倍。s TSH、FT3均值增高 ,FT4、Tg及 RIU曲线均明显降低。结论　 1全民食盐加碘前合肥市儿童垂体—甲状腺功能呈高代偿、高反应状态。 2全民食盐加碘后儿童垂体—甲状腺功能处于更高的代偿状态 ,并有亚临床甲状腺功能低下存在。3儿童垂体—甲状腺功能改变的始动因素是碘盐。 4须加强盐碘合理含量。Objective A studies on status of hypophysis thyroid function of children aged 7~14 were carried out from Hefei city before and after the one year's implementation of universal salt iodization (USI).Methods Comparison and analysis.Results Functional state of hypophysis thyroid axis was high compensatory,and subclinic hypothyroidism is presence also.Conclusions The effect of prevention for IDD was significant after one year's USI.But the hypophysis thyroid axis functional compensation is higher than that in last year.It was indicated that the subclinical hypothyroidism is presence.

关 键 词：碘盐 儿童 甲状腺功能 TRH-ST 碘缺乏病 

分 类 号：R725.911[医药卫生—儿科]