^(99m)Tc-MIBI心/肝比值对肝硬化患者的预后评价  

Prognostic evaluation of heart-liver ratio of ^(99m)Tc-MIBI on liver cirrhosis

作　　者：张玉军[1] 刘天舒[2] 陈世耀[2] 王吉耀[2] 

机构地区：[1]山东淄博矿务局中心医院消化内科,255120 [2]上海医科大学中山医院消化科,上海200032

出　　处：《中华肝脏病杂志》2000年第5期264-265,共2页Chinese Journal of Hepatology

摘　　要：目的评价^(99m)Tc－MIBI心／肝比值（H／L）对肝硬化患者预后判断。方法用回顾性队列研究方法，对所有进行H／L测定的肝硬化患者对其不同的Child－Pugh分级的H／L进行生存率分析。结果所有患者随访0.1～63个月，Child-PughA、B、C组的H／L值分别为0.85±0.15,0.99±0.19，1.15±0.27（F＝5.09P＜0.01），H／L≤1.0组的6个月、1年、2年的生存率明显较H／L儿＞1.0组高（分别为：85.9％，57．4％，57.4％和50.0％，39．4％，19．7％，P＜0．01），在Child－PughC级的患者中H／L≤1．0组的6个月、1年、2年的生存率明显较H／L＞1．0对组高（分别为71．4％，42．9％，42．9％和27．3％，18．2％，0）。结论H／L是评价肝硬化患者预后的较为有效的指标，可以和Child－Pugh分级相互补充。Objective To evaluate heart-liver ratio (H/L) of ^(99m)Tc-MIBI on the prognosis of cirrhotic patients.Methods Retrospective cohort study was used to analyze the survival rate among the patients who had received H/Ldetection, and the H/L value was classified by Child-Pugh class. Results All the patients were followed up for 0.1~63 months.H/L ratio was significantly different among Child-Pugh A, B, C groups (0.85 ± 0.15,0.99 ± 0.19, 1.15 ± 0.27, F=5.09, P<0.01); 6-month, 1 -year, and 2-year survival rates in H/L<1 .0 group were significantly higher than those in H/L >1.0 group (85.9%, 57.4%,57.4% vs 50.0%, 39.4%, 19.7%, P<0.01). Among patients with Child-Pugh degree C, 6-month, 1-year, and 2-year survivalrates in H/L<1 .0 group were significantlIy higher than those in H/L>1.0 group (71.4%, 42.9%, 42.9% vs 27.3%, 18.2%, 0). Con-clusion H/L is an effective index for evaluating prognosis of cirrhotic patients, and it could be complemented by Child-Pugh classification.[

关 键 词：肝硬化 放射性核显像 ^99MTC-MIBI 心/肝比值 

分 类 号：R575.204[医药卫生—消化系统] R817.45[医药卫生—内科学]