微波天线灭活在脊柱转移癌手术中的初步应用  

A primary research of microwave-induced hyperthermia in the management of malignant spine metastatic carcinoma

作　　者：柯晋[1] 张余[1] 张涛[1] 徐亮[1] 黄华扬[1] 尹庆水[1] 夏虹[1] 

机构地区：[1]广州军区广州总医院骨科医院,510010

出　　处：《实用医学杂志》2013年第17期2848-2850,共3页The Journal of Practical Medicine

基　　金：全军医学科研"十二五"面上课题(编号:CWS11C268);广东省科技计划课题(编号:2007A060101003;2008A060101004)

摘　　要：目的：评价微波灭活在脊柱转移性骨肿瘤手术中的初步临床效果。方法：对2009年4月至2011年4月收治的3例脊柱转移性骨肿瘤病例。应用术中微波天线灭活技术，回顾性分析术中失血量及手术时间、术后半年以上随访时的疼痛情况、Frankel神经功能以及生活质量情况。结果：3例患者术中平均失血量1100mL，手术时间平均5h，术后随访1～2年，所有患者均存活，随访1年时疼痛症状消失或减轻，运动功能均有不同程度的改善，生活质量水平较术前显著提高。结论：合理的病例选择结合微波灭活的手术可在一定程度上有效地灭活脊柱肿瘤，获得满意的治疗效果，但远期效果有待进一步观察。Objective To evaluate the primary clinical effect of hyperthermia induced by microwave in the treatment of malignant spine meatstatic carcinoma. Methods The retrospective study included 3 patients with malignant spine metastatic carcinoma who had undergone microwave-induced hyperthermia during the period of April 2009 to April 2011 were included in the study. The surgical duration, intraoperative blood loss, pain level six months after surgery, recovery of neurological function, and quality of life were analyzed postoperatively. Results The mean volume of blood loss was 1 100 mL, the surgical duration was 5 hours. All patients survived during a follow-up of one to two years. Pain was disappeared or alleviated, neurological functioin was improved, and quality of life was significantly elevated. Conclusions Rational selection of patients combined by microwave- induced hyperthermia can effectively destroy malignant spine metastatic carcinoma and achieve a satisfactory efficacy ; however, the long-term efficacy is still needed to be further assessed.

关 键 词：肿瘤转移 脊柱 微波 手术 

分 类 号：R738.1[医药卫生—肿瘤]