工作场所化学物质DNA损伤的早期检测  

Early detection of DNA damage by chemicals in workplace

作　　者：朱超[1] 韩雪莲[1] 袁翠英[2] 祝海珍[1] 朱方艳[1] 

机构地区：[1]江苏省安全生产科学研究院,江苏南京210042 [2]南京市鼓楼医院,江苏南京210008

出　　处：《中国工业医学杂志》2013年第4期266-268,共3页Chinese Journal of Industrial Medicine

摘　　要：化学物质的遗传毒性对人体的远期影响难以估量,因此,对DNA损伤进行及时检测,对损伤防治具有重要意义。本文拟对目前常用的DNA损伤检测方法进行简介及评价。The genetic toxicity of chemicals has long-term effects on human body, so the prompt detect of DAN damage would be very important for the prevention of the further injury. This paper will give a brief introduction and assessment on the commonly used DNA damage detection methods.

关 键 词：DNA损伤 单细胞凝胶电泳 微核试验 姐妹染色体互换 磷酸化组蛋白(γ-H2AX) 

分 类 号：R115[医药卫生—公共卫生与预防医学]