肠易激综合征与抑郁、焦虑障碍的关系  

Relationship between irritable bowel syndrome and depression/anxiety disorders

作　　者：元静[1] 刘小彦[1] 王敏[2] 王嫱[2] 李培凯[1] 苏萍[1] 侯瑜[1] 杨帆[1] SUNG-CHAN Paulin 杨建中[1] 

机构地区：[1]云南省第二人民医院临床心理科,昆明650000 [2]云南省第二人民医院消化科,昆明650000 [3]香港理工大学应用社会学系

出　　处：《临床精神医学杂志》2013年第4期233-234,共2页Journal of Clinical Psychiatry

基　　金：2009年度国家科技支撑计划(2009BAI77B05);香港理工大学研究基金(RGC on Poly U G-U430)

摘　　要：目的:探讨肠易激综合征(IBS)与抑郁、焦虑的关系。方法:采用美国精神障碍手册第4版(DSM-IV)轴I为诊断标准的临床结构式访谈工具(SCID-I-P)、抑郁自评量表(SDS)、焦虑自评量表(SAS)对126例IBS患者(IBS组)进行评估,并与126名正常对照者(对照组)比较。结果:IBS组的SDS、SAS标准分显著高于对照组(P均<0.001);IBS组抑郁/焦虑障碍发生率为4.76%(6例),其中1例IBS发病前诊断为焦虑障碍;抑郁和/或焦虑状态的发生率(52.4%,66例)明显的高于对照组(34.9%,44人)(P<0.01)。结论:IBS不是焦虑或抑郁障碍的延续,抑郁和/或焦虑障碍的发生与IBS密切相关。Objective：To explore the relationship between irritable bowel syndrome （IBS） and depression/anxiety disorders.Method：The structured clinical interview Axis I disorders （SCID-I-P） of manual of mental disorders IV （DSM-IV）,self-rating anxiety scale（SAS） and self-rating depression scale（SDS） were used to assess the depression and anxiety disorders in 126 patients with IBS（IBS group）,the results were compared with 126 healthy controls（control group）.Results：The standard scores of SDS and SAS in IBS group were significantly higher than control group（all P0.001）.The incidence of depression/anxiety disorder in IBS group was 4.76%（6 cases）,only 1 case diagnosed anxiety disorder was prior to the onset of IBS.The incidence of depression and/or anxiety state in IBS group （52.4%,66 cases）was significantly higher than control group （34.9%,44 cases）（P0.01）.Conclusion：IBS is not the continuation of depression/anxiety disorder,but occurrence of depression/anxiety is closely associated with IBS.

关 键 词：肠易激综合征 焦虑 抑郁 

分 类 号：R749.4[医药卫生—神经病学与精神病学]