前房注气对白内障囊外摘除术后早期角膜内皮影响  

The early effects of fdtered air bubble after manual small incision cataract surgery on corneal endotheHum

作　　者：张明悦[1] 刘金华[1] 杨勇[1] 刘铮[1] 彭鹏[1] 

机构地区：[1]广西医科大学附属第一医院眼科,南宁530021

出　　处：《中国实用眼科杂志》2013年第8期986-989,共4页Chinese Journal of Practical Ophthalmology

摘　　要：目的探讨小切口白内障囊外摘除术毕，前房注入滤过空气对角膜内皮细胞的早期影响。方法前瞻性临床病例对比研究。对2011年12月至2012年8月在广西医科大学附属第一医院眼科就诊的46例60只眼年龄相关性白内障患者，随机分成两组行小切口白内障囊外摘除术，实验组24例（30只眼）术毕前房注入滤过空气，对照组22例（30只眼）术毕平衡盐溶液维持前房。术前各眼角膜内皮细胞的参数在同龄人正常范围内。行实验组和对照组术前、术后角膜内皮细胞各参数的组内和组间比较。结果（1）术后1d，实验组角膜内皮细胞密度、六角形细胞百分比高于对照组，细胞变异系数、细胞平均面积低于对照组，差异有统计学意义（P〈0．05）。（2）实验组术后1、3、5d组内对比，角膜内皮各参数差异无统计学意义（P〉0．05）；（3）对照组术后1d细胞变异系数高于术后3、5d，平均细胞面积高于术后3d，六角形细胞百分数低于术后3、5d，差异有统计学意义（P〈0．05）。结论小切口白内障囊外摘除术毕，前房注入滤过空气对角膜内皮细胞早期无损伤。Objective To observe the early impact of injecting filtered air into anterior chamber on cornea endothelial cell after manual small incision cataract surgery （MSICS）. Methods A pro- spective randomized case-control study. Forty-six patients with age-related cataract （60 eyes） were ran- domly divided into two groups to undergo MSICS, for 24 patients （30 eyes） in the experimental group, filtered air was injected into anterior chamber after operation, while for 22 patients （30 eyes） in the control group, balanced salt solution was used to maintain anterior chamber after operation, the parameters of each cornea endothelial cell were in the normal range among peers. The corneal endothelial cell density （CED）, average cell size （AVG）, coefficient of variation in cell size （CV）, percentage of hexagonal cells （PHC） were compared before and after operation for the experimental group and the control group. Results On the first day after operation, the CED and the PHC in the experimental group were higher than that in the control group, while the CV and the AVG were lower than that in control group, with statistical significance （P 〈0.05）. On the first day, the third day and the fifth day after operation, the differences in all the parameters of cornea endothelial cell in the experimental group were not statistically significant （P 〉0.05）. On the first day after opera- tion, the CV in the control group was higher than that on the third day and the fifth day, and the AVG was higher than that on the third day, with statistical significance （P 〈0.05）, while the PHC in the control group was lower than that on the third day and the fifth day, with statistical significance（P 〈0.05）. Conclusions In the early days, there is no damage on cornea endothelial cell when filtered air is injected into anterior chamber after manual small incision cataract surgery.

关 键 词：小切口白内障囊外摘除术 滤过空气 角膜内皮 

分 类 号：R779.66[医药卫生—眼科]