肝脏血管平滑肌脂肪瘤的临床病理学特征分析  

Clinicopathological Study of 6 Cases of Liver Angiomyolipoma

作　　者：李桂梅[1] 常建宁 曹晓卉[1] 梅佳[1] 

机构地区：[1]中国人民解放军第八一医院病理科 [2]南京市朱庄94915部队卫生所

出　　处：《实用癌症杂志》2013年第3期298-300,共3页The Practical Journal of Cancer

摘　　要：目的探讨肝脏血管平滑肌脂肪瘤的临床病理学特点。方法回顾性分析6例肝脏血管平滑肌脂肪瘤的临床、影像学及病理学资料。结果该病女性多见,年龄27～58岁(平均38.7岁),3例患者是乙型肝炎病毒携带者。患者大多数无明显症状,肝功能和血清中甲胎蛋白和癌胚抗原水平均正常。肿瘤组织内可见不同比例的平滑肌、脂肪组织和血管成分,瘤细胞免疫组化标记HMB45和SMA表达阳性。患者均行部分肝切除术,术后随访6～43个月未出现复发和转移。结论肝脏血管平滑肌脂肪瘤术前诊断困难,确诊主要依靠特异的病理组织学改变,患者预后大多良好,但有复发和转移的可能,术后需长期随访。Objective To discuss the clinical and pathological features of patients with hepatic angiomyolipom.Methods The clinical,imaging,and pathological features of 6 patients with hepatic AML were retrospectively reviewed.Results There was marked female predominance in this disease.The median age was 38.7 years old with a range from 27 to 58.Three patients were hepatitis B-virus carriers.Most patients（4/6） did not have obvious symptom.Liver function and the levels of α-FP and CEA in plasma was normal in all patients.All tumors were composed of varied proportions of smooth muscle,adipose tissue,and blood vessels,and showed positive for HMB-45 and SMA by immunohistochemical staining.All patients underwent partial hepatectomy and there was no recurrence and metastasis during the follow-up from 6 months to 43 months.Conclusion The preoperative diagnosis is difficult.Definite diagnosis of this tumor is depandent on peculiar pathologic characteristic.The tumour may recur and metastize,so the long-time observation is necessary.

关 键 词：肝脏 血管平滑肌脂肪瘤 病理学 

分 类 号：R735.7[医药卫生—肿瘤]