声触诊组织量化技术评价慢性肝纤维化的初步研究  

Virtual Touch Quantification in the Evaluation of Chronic Liver Fibrosis

作　　者：雷志辉[1] 王少特[1] 金鹏[1] 刘欣[1] 陈超[1] 陈文卫[2] 

机构地区：[1]武警湖北省总队医院超声科,湖北武汉430061 [2]武汉大学人民医院超声科,湖北武汉430060

出　　处：《医学新知》2013年第4期273-274,278,共3页New Medicine

摘　　要：目的探讨声触诊组织量化技术检测慢性肝纤维化的价值。方法使用西门子超声的声触诊组织量化技术检测190例受检者的肝右叶，包括健康患者90例，乙肝阳性而无肝硬化患者60例和乙肝肝硬化患者40例，比较3个组受检者的弹性参数值。结果3个组受检者的肝右叶感兴趣区弹性参数有显著差异（P〈0．001），随着慢性肝病程度加重，弹性参数增高，两者有一定的相关性。结论声触诊组织量化技术可以无创评价肝弹性硬度，间接评估肝纤维化，具有一定的临床应用价值。Objective To evaluate the value of virtual touch quantification（VTQ） technique in chronic liver fibrosis. Methods Stiffness of the right lobe liver was examined with Acuson $2000 ultrasound system in 190 patients, including healthy people （ n = 90）, patients with hepatitis B virus （ without liver cirrhosis, n = 60） and patients with liv- er cirrhosis（n =40）. The elastic parameter values were compared in three groups. Results There were significant differences in elastic parameter values among three groups（ P 〈 O. 001 ）. Elastic parameter values increased along with the exacerbation of chronic liver diseases. Conclusion VTQ technique can assess the stiffness of liver noninvasively and evaluate the degree of liver fibrosis indirectly,which has a certain clinical value.

关 键 词：声触诊组织量化 肝纤维化 肝硬化 

分 类 号：R575[医药卫生—消化系统]