老年高血脂性急性胰腺炎患者行血浆置换法术后的临床效果分析74例  

Therapeutic effect of plasma exchange in treatment of hyperlipidemic acute pancreatitis in elderly patients:An analysis of 74 cases

作　　者：赵爱荣[1] 张慧[2] 田晓华[2] 刘阳[2] 刘卫荣[2] 

机构地区：[1]唐山工人医院护理部,河北省唐山市063000 [2]唐山工人医院重症医学科,河北省唐山市063000

出　　处：《世界华人消化杂志》2013年第23期2355-2358,共4页World Chinese Journal of Digestology

摘　　要：目的:探讨血浆置换法(plasma exchange,PE)治疗老年高血脂性急性胰腺炎(acute pancreatitis,AP)的疗效及护理体会.方法:随机选取我院在2011-04/2013-04收治的老年高血脂性AP患者74例,随机分为对照组和治疗组,对照组进行常规药物治疗,治疗组在常规药物的基础上使用PE治疗,检测患者的临床疗效,并总结护理体会.结果:经治疗后72 h,患者临床症状改善明显,心率(heart rhythm,HR)降低至正常,APACHEⅡ评分下降明显(P<0.05);血清三酰甘油(triacylglycerol,TG)、白介素-6(interleukin-6,I L-6)及肿瘤坏死因子-(t u m o r n e c r o s i s factor-,TNF-)亦明显下降(P<0.05).对照组总有效率为78.38%,治疗组总有效率为94.59%,两组间差异显著(2=4.1625,P<0.05).结论:老年高血脂性AP患者经PE治疗,并精心观察与护理,就可以得到很好的治愈.AIM： To investigate the therapeutic effects of plasma exchange （PE） in the treatment of hy- perlipidemic acute pancreatitis （HLP） in elderly patients. METHODS： Seventy-four elderly patients with HLP who were treated at our hospital from April 2011 to April 2013 were randomly divided into either a control group or a treatment group. The control group was given routine drug treat- ment, and the treatment group underwent PE on the basis of routine drug treatment. Clinical efficacy of PE was assessed.RESULTS： Clinical symptoms of patients in the treatment group improved significantly 72 h after treatment. For example, heart rate decreased to the normal level, APACHE II score and serum levels of triacylglycerol, interleukin-6 and tumor necrosis factor-a decreased significantly （all P 〈 0.05）. The total effective rate was significantly higher in the treatment group than in the control group （94.59% vs 78.38%, 1（2 = 4.1625, P 〈 0.05）. CONCLUSION： PE is effective in the treatment of HLP in elderly patients.

关 键 词：高脂血症 急性胰腺炎 血浆置换 护理体会 

分 类 号：R576[医药卫生—消化系统]