Histopathological Observation of Colibacillosis in Laying Hens  

育成蛋鸡大肠杆菌病的病理组织学观察(英文)

作　　者：沈萍[1] 张艳英[1] 何立宁 高桂生[1] 史秋梅[1] 高光平[1] 邵欣华[3] 郝佳科[1] 

机构地区：[1]河北科技师范学院,动物科技学院,河北省预防兽医学重点实验室,河北昌黎066600 [2]石家庄市兽药监察所,河北石家庄050049 [3]河北新华科极兽药有限公司,河北栾城051430

出　　处：《Agricultural Science & Technology》2013年第8期1167-1170,共4页农业科学与技术（英文版）

基　　金：科技部农业成果转化项目(2012GB2A200044);石家庄市科技局支撑计划(11150093A);秦皇岛市科技发展计划(201101A182)~~

摘　　要：[Objective] This study aimed to investigate the histopathological changes of hens with colibacillosis.[Method] Epidemiological investigation,clinical symptoms observation,pathological autopsy,laboratory diagnosis and paraffin-embedded tissue section were performed to diagnose the laying hens from a farm in Changli County,affected by a disease similar to pericarditis and perihepatitis in clinical symptoms.[Result] The pathogen isolated from those hens was E.coli.The histopathological changes of the diseased hens included myocardial cell degeneration and inflammatory cell infiltration in heart,fibrotic perihepatitis,necrotic hepatitis in liver,decreased lymphoid cells and inflammatory cell infiltration in spleen,lung congestion,lung room full of erythrocytes,hyaline degeneration in glomerular capillary and small intestinal epithelial cell shedding.[Conclusion] This study will provide scientific basis for the diagnosis and control of colibacillosis in poultry.[目的]深入了解鸡大肠杆菌病的病理组织学变化。[方法]试验采用流行病学调查、临床症状观察、病理剖检观察、实验室诊断和石蜡组织切片制作等方法对昌黎县某鸡场发生的一起蛋鸡以心包炎、肝周炎为主要特征的疾病进行诊断和病理组织学观察。[结果]试验分离到的病原菌为大肠杆菌;患病蛋鸡的病理组织学变化表现为:心脏呈心肌细胞变性、炎性细胞浸润;肝脏呈纤维素性肝周炎和坏死性肝炎;脾脏呈淋巴细胞减少、炎性细胞浸润;肺脏呈充血、淤血,肺房内存在红细胞;肾小球毛细血管透明变性;小肠粘膜上皮细胞脱落。[结论]该研究为鸡大肠杆菌病的诊断和防治提供了科学依据。

关 键 词：HEN COLIBACILLOSIS HISTOPATHOLOGY ORGAN 

分 类 号：S858.31[农业科学—临床兽医学]