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作品数：467被引量：921H指数：13
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Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease
《Neural Regeneration Research》2025年第10期2982-2997,共16页Hongli Li Jianhua Huang Di Zhao Lemei Zhu Zheyu Zhang Min Yi Weijun Peng 
financially supported by the National Natural Science Foundation of China,No.823 74552 (to WP);the Science and Technology Innovation Program of Hunan Province,No.2022RC1220 (to WP);the Natural Science Foundation of Hunan Province of China,Nos.2020JJ4803 (to WP),2022JJ40723 (to MY);the Scientific Research Launch Project for New Employees of the Second Xiangya Hospital of Central South University (to MY)
Alzheimer’s disease not only affects the brain,but also induces metabolic dysfunction in peripheral organs and alters the gut microbiota.The aim of this study was to investigate systemic changes that occur in Alzhei...
关键词：Alzheimer’s disease APP/PS1 mice brain-kidney axis gut microbiota heart-brain axis liver-brain axis lung-brain axis microbiota-gut-brain axis peripheral organ metabolism spleen-brain axis 
B-class floral homeotic gene MapoAPETALA3 may play an important role in the origin and formation of multi-tepals in Magnolia polytepala
《Horticultural Plant Journal》2025年第2期891-905,共15页Liyong Sun Yao Chen Tangjie Nie Xiaoxia Wan Xuan Zou Zheng Jiang Huilin Zhu Qiang Wei Yaling Wang Shuxian Li Zengfang Yin 
supported by grants from the Postgraduate Research&Practice Innovation Program of Jiangsu Province(Grant No.KYCX19_1080);A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);the Doctorate Fellowship Foundation of Nanjing Forestry University。
In angiosperms,floral architecture diversity reflects its significance in exploring plant evolution.Magnolia polytepala,an endemic and ancient species in China,possesses a unique multi-tepal trait.Notably,the origin a...
关键词：Magnolia polytepala Doubleflower Transcriptional regulation Organ initiation MapoAP3 
3D printing for tissue/organ regeneration in China
《Bio-Design and Manufacturing》2025年第2期169-242,I0001,I0002,共76页Chaofan He Jiankang He Chengtie Wu Changshun Ruan Qi Gu Yongqiang Hao Yang Wu Shuo Bai Xiaoxiao Han Liliang Ouyang Jun Yin Hongzhao Zhou Zhuo Xiong Maobin Xie Lei Shao Jing Nie Liang Ma Cijun Shuai Changchun Zhou Xin Zhao Xuetao Shi Mengfei Yu Jiayin Fu Peng Wen Huixia Xuan Yuan Pang Yan’en Wang Yuan Sun Ziqi Gao Abdellah Aazmi Jingbo Zhang Tianhong Qiao Qixiang Yang Ke Yao Mao Mao Jianxin Hao Pinpin Wang Jirong Yang Huawei Qu Xinhuan Wang Xin Liu Shen Ji Shasha Liu Jingke Fu Bingxian Lu Mohan Wu Feng Chen Zihao Zheng Boqing Zhang Muyuan Chai Chaoying Zhang Mouyuan Sun Bo Peng Huayong Yang Yong He 
supported by the National Natural Science Foundation of China(Nos.52325504,52235007,and T2121004).
As surgical procedures transition from conventional resection to advanced tissue-regeneration technologies,human disease therapy has witnessed a great leap forward.In particular,three-dimensional(3D)bioprinting stands...
关键词：3D printing BIOPRINTING Tissue engineering Regenerative medicine 
Extended travel for donor organs:Is cold static storage still relevant
《World Journal of Transplantation》2025年第3期164-174,共11页Montana Reynolds Martin Gerard Walsh Ervin Y Cui Divyaam Satija Doug A Gouchoe Matthew C Henn Kukbin Choi Nahush A Mokadam Asvin M Ganapathi Bryan A Whitson 
Supported by The Jewel and Frank Benson Family Endowment;and The Jewel and Frank Benson Research Professorship.
BACKGROUND Traditional limitations of cold static storage(CSS)on ice at 4℃during lung transplantation have necessitated limiting cold ischemic time(CIT)to 4-6 hours.Ex vivo lung perfusion(EVLP)can extend this preserv...
关键词：Transplantation lung Ex vivo lung perfusion Ischemic time Machine perfusion United Network for Organ Sharing Cold static storage Normothermic perfusion 
Liver as a new target organ in Alzheimer's disease:insight from cholesterol metabolism and its role in amyloid-beta clearance
《Neural Regeneration Research》2025年第3期695-714,共20页Beibei Wu Yuqing Liu Hongli Li Lemei Zhu Lingfeng Zeng Zhen Zhang Weijun Peng 
financially supported by the Science and Technology Innovation Program of Hunan Province,No.2022RC1220(to WP);China Postdoctoral Science Foundation,No.2022M711733(to ZZ);the National Natural Science Foundation of China,No.82160920(to ZZ);Hebei Postdoctoral Scientific Research Project,No.B2022003040(to ZZ);Hunan Flagship Department of Integrated Traditional Chinese and Western Medicine(to WP)。
Alzheimer's disease,the primary cause of dementia,is characterized by neuropathologies,such as amyloid plaques,synaptic and neuronal degeneration,and neurofibrillary tangles.Although amyloid plaques are the primary ch...
关键词：ABCA1 Alzheimer's disease AMYLOID-BETA apolipoprotein E cholesterol metabolism LIVER liver X receptor low-density lipoprotein receptor-related protein 1 peripheral clearance tauroursodeoxycholic acid 
Concurrent pediatric eosinophilic esophagitis and inflammatory bowel disease:a longitudinal single center case-control study and literature review
《World Journal of Pediatrics》2025年第2期199-207,共9页Alexandra S.Hudson Michael Pickens Dale Lee Kendra L.Francis David L.Suskind Ghassan Wahbeh Hengqi Betty Zheng 
The incidence of chronic immune-mediated diseases is increasing worldwide across all age groups,affecting more than 10%of the general population[1,2].Immune-mediated diseases are also more likely to be associated with...
关键词：pathophysiologies organ overlap concurrent disorders eosinophilic e immune mediated diseases inflammatory bowel disease bowel disease ibd eosinophilic esophagitis 
Two cases of complex traumatic aortic dissection combined with multiple organ injuries
《Chinese Journal of Traumatology》2025年第1期29-34,共6页Qingpeng Song Lili Bao Xuejun Wu Bingqi Liu Maohua Wang 
Traumatic aortic injury(TAI)is an acute,critical,and severe disease,and then combined with multiple organ damage,it is even more dangerous.TAI progresses very rapidly,with a pre-hospital mortality rate of 57%-80%,and ...
关键词：Traumatic aortic injury Multi-organ failure Endovascular surgery 
Organ Preservation:History,Advancements,and Perspectives
《Engineering》2025年第1期112-134,共23页Xinmeng Liu Zhiquan Shu Liming Zhang Haoyue Li Jing Yang Lei Zhang 
financially supported by the National Key Research and Development Program of China(2022YFC2100800);the National Natural Science Foundation of China(22478296,22078238,52373117,and U23B20121);the Haihe Laboratory of Sustainable Chemical Transformations(24HHWCSS00005);the Open Funding Project of the National Key Laboratory of Biochemical Engineering。
Recent advances in organ transplantation,regenerative medicine,and drug discovery have emphasized the critical importance of effective preservation techniques for organs.Despite these advances,current preservation tec...
关键词：Organ preservation Organ machine perfusion Static cold storage VITRIFICATION Preservation solution 
Precision oncology: The role of minimally-invasive ablation therapy in the management of solid organ tumors
《World Journal of Radiology》2025年第1期1-18,共18页Farbod Fazlollahi Mina S Makary 
Solid organ tumors present a significant healthcare challenge,both economically and logistically,due to their high incidence and treatment complexity.In 2023,out of the 1.9 million new cancer cases in the United State...
关键词：MINIMALLY-INVASIVE Non-invasive Solid organ tumor Ablation LOCOREGIONAL 
Patients admitted in the intensive care unit after solid organ or bone marrow transplantation:Retrospective cohort study
《World Journal of Transplantation》2025年第1期95-104,共10页Ana Vujaklija Brajkovic Iva Kosuta Lucija Batur Sara Sundalic Marijana Medic Andro Vujevic Luka Bielen Jaksa Babel 
BACKGROUND Solid organ transplantation(SOT)and hematopoietic stem cell transplantation(HSCT)revolutionized the survival and quality of life of patients with malignant diseases,various immunologic,and metabolic disorde...
关键词：Liver transplantation Kidney transplantation Hematopoietic stem cell transplantation Critical care SEPSIS Septic shock MORTALITY 
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