中文版统一肝豆状核变性评分量表的信度和效度的研究  

Study of reliability and validity of Chinese version of united Wilson's disease rating scale

作　　者：韩永升[1] 王训[1] 韩咏竹[1] 陈林[1] 徐银[1] 王伟[1] 汪炜民[1] 马心锋[1] 胡纪源[1] 杨任民[1] 

机构地区：[1]安徽中医学院神经病学研究所附属医院神经内科,合肥230061

出　　处：《临床神经病学杂志》2013年第4期241-243,共3页Journal of Clinical Neurology

摘　　要：目的研究中文版统一肝豆状核变性评分量表（UWDRS）的信度和效度。方法采用翻译和回译将UWDRS翻译为中文版本。应用中文版UWDRS评价110例肝豆状核变性（HLD）患者，评价其信度和效度。结果中文版UWDRS量表总分为31．27（20．656，0～89），神经功能得分为17．53（15．867，0～64），肝脏功能得分为6．46（6．150，0～36），精神症状得分为7．27（6．045，0～26）。量表整体Cronbachd系数为0．967，神经功能为0．975、肝脏功能为0．493、精神症状为0．798。总量表Spearman．Brown系数为0．811，神经功能为0．941，肝脏功能为0．392，精神症状为0．775。总量表2次测定的重测相关系数为0．968，神经功能为0．970、肝脏功能为0．628、精神症状得分为0．823（均P〈0．001）；总量表的两位评定者间相关系数为0．920，神经功能为0．927，肝脏功能为0．584，精神症状得分为0．676（均P〈0．001）。结构效度没有只出现3个明确的因子，但有6个因子解释了总变异的50．685％。总量表的平均量表水平内容效度指数（S-CVI／Ave）值为0．99。结论中文版UWDRS具有良好的信度和效度，但部分内容尚需进一步修订。Objective To evaluate the reliability and validity of the Chinese version of the united Wilson＇s disease rating scale （UWDRS）. Methods The Chinese version of UWDRS was developed by translation and back translation. One hundred and ten patients with hepatolenticular degeneration （HLD） were evaluated by Chinese version of UWDRS, and the reliability and validity of the scale were evaluated. Results The total score of Chinese version of UWDRS was 31.27 （20. 656,0 - 89）, neurological function score was 17.53 （ 15. 867,0 - 64）, liver function score was 6.46 （6. 150,0 -36）, mental symptom score was 7.27 （6. 045,0 -26）. Cronbach＇s coefficient of the entire scale was 0. 967, and neurological subscale was 0. 970, hepatic subscale was 0. 493, psychiatric subscale was 0. 798. The Spearman-Brown coefficient of the entire scale was 0. 811, and neurological subscale was 0. 941, hepatic subscale was 0. 392, psychiatric subscale was 0. 775. The coefficient of test-retest reliability was 0. 968, and neurological subscale was 0. 970, hepatic subscale was 0. 628, psychiatric subscale was 0. 823 （ all P 〈 0. 001 ）. The coefficient of inter-rater reability was 0. 920, and neurological subscale was 0. 927, hepatic subscale was 0. 584, psychiatric subscale was 0. 676 （ all P 〈 0. 001 ）. An explorative factor analysis with varimax rotation did not yield a clear three-factorial solution, but a solution with six interpretable factors explained about 50. 685% of the variance. The average of scale-levelcontent validity index was 0. 99. Conclusion Chinese version of UWDRS has high reliability and validity. But it still need to be revised.

关 键 词：中文版统一肝豆状核变性评分量表 信度 效度 

分 类 号：R742.4[医药卫生—神经病学与精神病学]