17例原发性肾肉瘤回顾性分析  

Retrospective analysis of primary renal sarcoma: 17 cases report

作　　者：林健[1] 张小平[2] 黄炳伟[1] 李森[1] 韩文科[1] 周利群[1] 何群[1] 李昕[1] 

机构地区：[1]北京大学第一医院泌尿外科,北京大学泌尿外科研究所,国家泌尿,男性生殖系肿瘤研究中心 [2]北京市丰台区长辛店医院泌尿外科,北京100034

出　　处：《北京大学学报（医学版）》2013年第4期554-557,共4页Journal of Peking University:Health Sciences

摘　　要：目的:总结原发性肾肉瘤的临床表现、治疗及预后,提高对该病的认识。方法:回顾性分析17例肾肉瘤的临床资料及随访结果。结果:16例患者行根治性肾切除术,1例因肺部转移灶行穿刺活检病理诊断梭形细胞肉瘤而行肾动脉栓塞及化疗,术后病理及免疫组化诊断为平滑肌肉瘤6例,恶性纤维组织细胞瘤3例,横纹肌肉瘤4例,血管外皮细胞瘤1例,透明细胞肉瘤1例,脂肪肉瘤1例,滑膜肉瘤1例。13例获得随访,存活7～132个月,获访者总的平均生存期为23.2个月。结论:肾肉瘤是肾肿瘤中的罕见类型,具有恶性程度高、进展快速、易转移、预后差及生存期短的临床特点,早期诊断及根治性切除能在一定程度上提高患者的生存率。Objective：To investigate the clinical characteristics,prognosis,survival and diagnosis of primary renalsarcoma.Methods：In the study,17 cases of renal sarcoma were reviewed and analyzed,the incidence,clinical manifestations,treatments and prognosis of renal sarcoma discussed and analyzed,and the correlated literature also reviewed.Results：Radical nephrectomy was the main treatment for 16 cases,one case was punctured and pathologized.The distributions of pathology were leiomyosarcoma,malignant fibrous histiocytoma,rhabdomyosarcoma,synoviosarcoma,liposarcoma,and clear-cell sarcoma.Thirteen of the subjects were followed-up,and the time of survival varied from 7 to 132 months.Conclusion： Renal sarcomas are rare and highly malignant and the prognosis is poor.Early diagnosis and radical nephrectomy can prolong the patient’s life.

关 键 词：肾肿瘤 肉瘤 肾切除术 预后 

分 类 号：R737.11[医药卫生—肿瘤]