颈内动脉颅内段常规头颅CT钙化斑块评分对其狭窄的筛检作用  

Screening Effect of the Intracranial Internal Carotid Artery's Plaque Calcium Score by Using Conventional Brain Unenhanced CT on Artery stenosis

作　　者：陈立勋[1] 张婷[2] 赵衡[1] 肖文连[1] 吴晓东[1] 刘进才[1] 游咏[3] 

机构地区：[1]南华大学附属第一医院放射科,湖南省衡阳市421000 [2]广州市越秀区疾病预防控制中心,广东省广州市510000 [3]南华大学附属第一医院神经内科,湖南省衡阳市421000

出　　处：《中国动脉硬化杂志》2013年第8期741-744,共4页Chinese Journal of Arteriosclerosis

摘　　要：目的探讨常规头颅CT平扫对颈内动脉颅内段钙化斑块评分及对该段血管狭窄程度的筛检作用。方法行头颈部CT动脉造影(含常规头颅CT平扫,CTA)的病例110例,按照目测和软件评分相结合的方法将斑块分为4级,选取能成功进行Agatston钙化评分的3、4级斑块并能进行CT动脉造影狭窄分析(AVA)的病例26例,记录斑块的Agatston钙化评分值;采用AVA软件分析该斑块的血管狭窄程度及相应的北美症状性颈动脉内膜切除术(NASCET)标准分级。结果 26例中,轻度狭窄18例,Agatston钙化评分值2.69±1.01;中度狭窄5例,Agatston钙化评分值5.25±0.88;重度狭窄及闭塞3例,Agatston钙化评分值6.80±0.30。中、重度狭窄与轻度狭窄的血管斑块Agatston钙化评分差异有统计学意义(P<0.05),中、重度狭窄之间差异无统计学意义(P>0.05)。狭窄程度与斑块的Agaston钙化评分正相关(r=0.938,P<0.05)。结论常规头颅CT平扫颈内动脉颅内段钙化斑块Agatston评分对该段血管狭窄程度有筛检作用,血管斑块Agatston钙化评分值5.25以上患者应进一步行CTA检查。Aim To investigate the preliminary scanning significance of artery stenosis with intracranial internal carotid artery＇ s plaque calcium score using conventional brain unenhanced computed tomography （CT）. Methods By retrospectively analyzing brain and neck CT artery imaging （including conventional brain unenhanced CT, CTA） of 110 cases, the intracranial internal carotid artery＇ s calcification were classified into 4 grades. Of them, there are 26 cases which can be successfully classified into 3/4 grade by Agatston Calcium Score and receive CT artery imaging analysis of vascular and artery （AVA） software. AVA software was used to analyse the calcification segment artery＇ s stenosis degree and its North American Symptomatic Carotid Endarterectomy Trial criteria （NASCET） classification. Results In the 26 cases, there are 18 cases of mild grade with Agatston Calcium Score 2. 69 _＋ 1.01,5 cases of moderate grade with Agat- ston Calcium Score 5.25 ＋ 0. 88, 3 cases of high grade with Agatston Calcium Score 6. 80 -＋ 0. 30. The difference between high, moderate grade and mild grade has statistic significance （ P 〈 0. 05 ）. The difference between high and moderate grade has no statistic significance （P 〉 0. 05 ）. There were positively significant correlation between stenosis degree and calcification＇ s Agatston Calcium Score （ r = 0. 938, P 〈 0. 05 ）. Conclusions Conventional brain unenhanced CT in- tracranial internal carotid artery＇ s Plaque Calcium Score can be used to scan artery stenosis, and the one with Agatston Calcium Score over 5.25 ±9. 88 is suggested to proceed CTA examination.

关 键 词：常规头颅CT平扫 颈内动脉颅内段 斑块Agatston钙化评分 动脉粥样硬化狭窄 

分 类 号：R741[医药卫生—神经病学与精神病学]