多发性骨软骨瘤病的^(99)Tcm-MDP全身骨显像分析  

^(99)Tcm-MDP whole body bone imaging in patients with multiple osteochondroma

作　　者：张连娜[1] 冯瑾[1] 陈瑞玲[1] 何海燕[1] 杨芳[1] 

机构地区：[1]北京积水潭医院核医学科,北京100035

出　　处：《医学影像学杂志》2013年第8期1297-1299,1303,共4页Journal of Medical Imaging

摘　　要：目的分析多发性骨软骨瘤病的99mTc-MDP全身骨显像的影像特点,评价骨显像在多发性骨软骨瘤病中的应用价值。方法回顾分析62例确诊为多发性骨软骨瘤病患者的临床、骨显像及其他影像学资料,总结多发性骨软骨瘤病的骨显像特点,并与其他影像学结果进行比较。结果 62例患者中,100%在身体不同地方发现无痛性骨性包块,其中17.7%伴有关节功能障碍,53.2%有家族史。骨显像发现全身骨骼受累最多的部位前三位分别为胫骨近端17.4%、股骨远端17.0%、股骨近端16.4%。受累最少的部位为颅骨0%。在所有病灶中,1级摄取病灶占全部病灶的7.9%(24/305)、2级摄取病灶占全部病灶的34.1(104/305)、3级摄取病灶占全部病灶的40.0%(122/305)、4级摄取病灶占全部病灶的18%(55/305)。结论多发性骨软骨瘤病的全身骨显像表现为长骨末端异常的、不规则的、多处的放射性浓聚,结合临床及其他影像学资料,99mTc-MDP全身骨显像可用于多发性骨软骨瘤病患者的诊断与鉴别诊断、随访以及肿瘤恶变的评价。[Abstract] Objective To investigate the usefulness of 99mTc-MDP whole body bone scintigraphy （WBBS） in patients with multiple osteochondroma. Methods 99mTc-MDP WBBS was performed in 62 patients with multiple osteochondroma. The typical scintigraphic manifestations of multiple osteochondroma were summarized and compared to other radiological imaging data. Results Among 62 patients, 100% of cases were associated with Painless bone mass; 17.7% accompanied by joint dysfunction, 53.2% had a family history. Bone scintigraphy found that the most common location of exostosis was juxta-epiphyscal regions of the long bones, no exostosis was found in skull. In all lesions, one grade of uptake accounted for 7.9%o of all lesions （24/305）, tone grade of uptake lesions accounted for 34.1 of all lesions （104/305）, 3 uptake le- sions accounted for 40.0% of all lesions （122/305）, four pickup lesions accounted for all lesions of 18% （55/305）. Conclusion Multiple osteochondromatosis showed irregular various radioactive concentration in end of long bones, 99mTc-MDP bone scintigraphy, which combined with clinical and radiological data, can be used to diagnose, differentiate, and localize the insidious lesion and evaluate the tumor malignant transformation in patients with multiple osteochondroma.

关 键 词：多发性骨软骨瘤病 全身骨显像 放射性核素 

分 类 号：R738.3[医药卫生—肿瘤] R815.2[医药卫生—临床医学]