阿司匹林相关性小肠溃疡致消化系出血、巨幼细胞贫血1例  

Aspirin-associated small intestinal ulcer with severe anemia as the first manifestation:A case report

作　　者：王柏清[1] 李甜甜[1] 孙光斌 

机构地区：[1]天津市第五中心医院消化科,天津市300450

出　　处：《世界华人消化杂志》2013年第24期2490-2492,共3页World Chinese Journal of Digestology

摘　　要：近几十年来随着非甾体类抗炎药物(nonsteroidal anti-inflammatory drugs,NSAIDs)应用越来越多,NSAIDs相关性肠病逐渐引起人们的重视.随着对NSAIDs相关性肠病的研究深入,人们逐渐认识到长期应用NSAIDs所引起的相关性肠病是小肠溃疡的一个重要原因.本文报道了1例长期服用阿司匹林的患者,以重度贫血为首发症状,血液及骨髓检查提示巨幼细胞贫血,胶囊内镜诊断为小肠溃疡.临床医生应提高对类似病例的认识和诊疗思路,避免误诊.Non-steroidal anti-inflammatory drugs （NSAIDs） are the most widely used medications for treat- ing inflammatory conditions. Recently, they are also used to prevent the progression of cardio- vascular disease and the pain of muscle, bones and arthrosis. However, long-term and generous use of NSAIDs may cause mucosal injury in the stomach and duodenum. Investigation of the cor- relation between NSAIDs and bowel enteropathy reveals that long-term application of NSAIDs play an important role in the development of small intestinal ulcers. Here we report a case of small intestinal ulcer with severe anemia as the first manifestation in a patient with long-term aspirin use. Blood and bone marrow examina- tions revealed megaloblastic anemia, and capsule endoscopy demonstrated small intestinal ulcer. Clinicians should improve the diagnosis and treatment of similar cases to avoid misdiagnosis.

关 键 词：阿司匹林 小肠溃疡 非甾体类抗炎药物相关性肠病 

分 类 号：R574[医药卫生—消化系统]