普通人群进食障碍患病率的系统综述(英文)  

Prevalence of eating disorders in the general population:a systematic review

作　　者：钱洁[1,2] 胡强[3] 万玉美[3] 李婷[3] 武牡丹[3] 任致群[1,2] 于德华[1,2] 

机构地区：[1]上海市杨浦区中心医院 [2]同济大学附属杨浦医院 [3]上海交通大学医学院附属精神卫生中心

出　　处：《上海精神医学》2013年第4期212-223,共12页Shanghai Archives of Psychiatry

基　　金：supported by the Research Leadership Development Plan of the city of Shanghai(XBR2011005)

摘　　要：背景：世界各地关于进食障碍的流行病学研究得到的患病率数据不尽一致，目前尚缺乏系统综述研究以明确这些差别的原因所在。目的：运用Meta分析的方法汇总不同地区普通人群进食障碍的患病率数据，以确定与患病率相关的因素。方法：系统检索PubMed／Medline、PsyclNFO、ISlwebofknowledge、Ovid、中国知识资源总库，中国科技期刊数据库，万方数据，中国生物医学文献服务系统的数据库，收集关于进食障碍患病率的文献，按照预先制定的纳入及排除标准筛选相关研究。采用R-2．15。2软件进行统计分析。结果：共检索到9315篇不重复的文献（约四分之一为中文文献），其中仅15项研究符合纳入标准，累计调查72961人。纳入的15项中无国内研究，仅一项来自于亚洲国家（韩国）。估计的进食障碍的终生患病率为1．01％（95％CI，0。54～1．89％），12个月患病率为0．37％（95％cl，0．22～0．63％），4周患病率为0．21％（95％CI，0。15～0．28％）。神经性厌食、神经性贪食、暴食性障碍的终生患病率分别为0．21％（95％Cl，0．11～0．38％）、O．81％（95％Cl，0．59～1．09％）、2．22％（95％CI，1．78～2。76％）。女性进食障碍终生患病率与男性之比为4．2。欧洲国家进食障碍的终生患病率约为韩国研究报告数据的6．1倍。随着时间推移，总的进食障碍患病率有所升高，但无统计学意义，但神经性厌食症的患病率有统计学意义的升高。结论：普通人群中进食障碍较为常见，女性比男性多，西方国家比亚洲国家多。可能由于进食障碍的诊断标准有了变动，近年来报道的患病率有增高趋势。研究局限性包括可获得的流行病学资料非常有限，不同研究中进食障碍包括的类别有所不同以。及缺少中低收入国家（包括中国）中合适的流行病学研究。Background： The estimated prevalence of eating disorders reported in community surveys from different parts of the world varies widely but there has been no systematic attempt to identify the reasons for these differences. Objective： Use meta-analysis methods to pool data from community surveys about the prevalence of eating disorders in different locations and to identify the factors that are associated with the reported prevalence of eating disorders. Methods： Based on pre-defined inclusion and exclusion criteria, studies were identified from the following databases： PubMed/Medline, PsyclNFO, ISI webof knowledge, Ovid, Chinese National Knowledge Infrastructure, Chongqing VIP database for Chinese Technical Periodicals, WANFANG DATA, and Chinese Biological Literature Service System. Statistical analysis was conducted using R software. Results： Among the 9315 unduplicated reports reviewed （one-fourth of which were published in Chinese） only 15 - with a pooled sample size of 72,961 individuals - met the inclusion criteria for the analysis. None of the included studies were from China and only one Asian country （South Korea） was included in the analysis. The estimated lifetime prevalence, 12-month prevalence, and 4-week prevalence of any eating disorder was 1.01% （95% confidence interval [CI], 0.54-1.89）, 0.37% （Cl, 0.22-0.63）, and 0.21% （CI, 0.15-0.28）, respectively. Estimated lifetime prevalence of anorexia nervosa, bulimia nervosa, and binge eating disorder was 0.21% （Cl, 0.11-0.38）, 0.81% （Cl, 0.59-1.09）, and 2.22% （Cl, 1.78-2.76）, respectively. The estimated female-male ratio for lifetime prevalence of any eating disorder was 4.2. The lifetime prevalence of any eating disorder reported from studies conducted in Western countries was 6.1-fold greater than that reported in a single study from South Korea. Over time there has been a non-significant increase in reported prevalence of any eating disorder and a significant increase in reported prevalence of anorexia nervosa.

关 键 词：服务系统 失调 饮食 人群 国家知识基础设施 MEDLINE META分析 PUBMED 

分 类 号：R749.7[医药卫生—神经病学与精神病学]