三种药物防治胃肠肿瘤化疗所致呕吐的临床研究  

The Clinical Research of Three Kinds of Drugs to Control Vomitting Caused by Chemical Therapy in the Patients with Tumor

作　　者：陈业希[1] 庄春柳[1] 郭国湖[1] 林李波[1] 夏仁品[1] 

机构地区：[1]汕头大学医学院第二附属医院外科,汕头515041

出　　处：《汕头大学医学院学报》2000年第3期41-42,共2页Journal of Shantou University Medical College

摘　　要：目的 :评价三种药物防治胃肠肿瘤化疗所致呕吐的价值。方法 :90名患者随机分成三组 ,灭吐灵组 (A组 ) ,吗丁啉组 (B组 ) ,枢丹组 (C组 )。应用 5 -Fu +LV方案化疗 5天 ,观察 5天内三种药物的止吐效果。结果 :A和B、C组比较有显著性差异 (P <0 0 5 ) ,B和C比较无显著性差异 (P >0 0 5 )。结论 :B组副作用少 ,疗效高 ,建议临床推广使用吗丁啉。Objective: To evaluate the three kinds of drugs to control vomitting caused by chemical therapy in the patients with tumor.Methods:Ninety patients were divided into three groups randomly—Domperidone(group A),Emetisan(group B) and Ondansetron(group C).5-Fu+LV was used for five days,and the vomitting controlled the effects of three drugs were observed within five days.Results:There was a marked difference between group A and B( P<0 05) and between group A and C,but no difference between group B and C(P>0 05).Conclusion:Emetisan is less side effects,cheap and effective.

关 键 词：灭吐灵 吗丁啉 枢丹 胃肠肿瘤 呕吐 药物疗法 

分 类 号：R735.05[医药卫生—肿瘤] R442.1[医药卫生—临床医学]