喉恶性淋巴瘤的临床特点及诊治策略  

Clinical features and treatment strategies of laryngeal malignant lymphoma: reports of 14 cases

作　　者：张凯[1] 陈文宽[2] 

机构地区：[1]汕头大学附属粤北人民医院肿瘤外科,广东韶关512026 [2]中山大学肿瘤防治中心头颈外科,广东广州510060

出　　处：《中国肿瘤外科杂志》2013年第4期218-220,共3页Chinese Journal of Surgical Oncology

摘　　要：目的探讨喉恶性淋巴瘤的临床特点及诊治方案。方法回顾性分析粤北人民医院自1988年2月至2009年12月间收治的14例喉恶性淋巴瘤患者的临床资料,同时结合复习国内外相关文献,总结喉恶性淋巴瘤的临床特点及诊治方案。结果 14例患者均经病理确诊为喉恶性淋巴瘤,首次确诊率为50%(7/14),未首次确诊患者确诊时间较长。确诊后13例患者行化疗和(或)放疗,1例行全喉切除术+放疗。随访1～15年,1、3、5年生存率分别为69.2%、53.8%和46.1%。结论喉恶性淋巴瘤的早期诊断和根据临床分期制定不同的治疗方案,对患者的预后及喉功能的保全有重要意义。Objective To evaluate clinical characteristics and treatment of laryngeal malignant lymphoma. Methods Of 14 patients with the diagnosis of lymphoma involving the larynx in our hospital during 1988 to 2009 were retrospectively reviewed. Details of the pathologic condition,the difficulties in diagnosis,and treatment were presented. Relative references at home and abroad were reviewed. Results 14 patients were proved pathologically to be laryngeal malignant lymphoma. 50% （ 7/14） of these cases were accurately diagnosed in the first diagnosis. It was challenged and time-consuming to accurately diagnose the other cases. 13 received nonoperative methods such as pure chemotherapy or chemo-radiotherapy. 1 case received operation ＋ radiotherapy. 13 patients received follow-up（ 1 to 15 years） ; 1,3,5-year survival rates were 69. 2% ,53. 8% and 46. 1% . Conclusions It is significant to diagnose early and choose different treatments depending on clinical stages for prognosis of patients and saving functions of larynx.

关 键 词：喉恶性淋巴瘤 临床特点 诊断 治疗 

分 类 号：R739.65[医药卫生—肿瘤]