经尿道电切术联合丝裂霉素灌注治疗非浸润性膀胱尿路上皮癌70例报告  

Transurethral Resection of the Bladder Tumor(TURBT)combining with Intravesical Mitomycin Perfusion for Non-invasive Bladder Urothelial Carcinoma-70 Cases Report

作　　者：罗德康[1] 王明祥[1] 王杰[1] 陈晓[1] 汪燕君[1] 

机构地区：[1]四川省第五人民医院泌尿外科,成都610031

出　　处：《肿瘤预防与治疗》2013年第4期229-230,共2页Journal of Cancer Control And Treatment

摘　　要：目的：探讨经尿道膀胱肿瘤电切术（TURBT）联合丝裂霉素膀胱灌注治疗非浸润性膀胱尿路上皮癌的临床疗效及并发症和不良反应.方法：采用TURBT联合丝裂霉素膀胱灌注治疗70例非浸润性膀胱尿路上皮癌患者,回顾性分析患者的临床病理资料.结果：一次性切除68例,分期切除2例,手术时间30分钟～60分钟,平均住院10天,无手术并发症发生.术后病理诊断移行细胞癌64例,乳头状癌6例,术后随访3个月～2年,8例复发,复发率为11.4％（8/70）.结论：TURBT联合丝裂霉素膀胱灌注治疗非浸润性膀胱尿路上皮癌效果良好,并发症少.Objective： To explore the clinical efficacy, complications and side effects of transurethral resection of the bladder tumor（TURBT） combining with intravesical mitomycin perfusion to treat non-invasive bladder urothelial carcinoma. Methods： Seventy patients with non-invasive bladder urothelial carcinoma were treated with TURBT combining with intravesical mitomycin perfusion. Clinical pathological data were analyzed retrospectively. Results ： Lesions of 68 cases were resected at the first TURBT and that of 2 ca- ses were totally resected by staged excision. The mean operating time was 30rain -60min, and the mean hospital stays was 10 days. No surgical related complications occurred. Sixty-four cases were diagnosed as transitional cell carcinorma and 6 cases as papillary carcino- ma by postoperative pathological analysis. The follow-up time was 3 months to 2 years. Recurrence occurred in 8 cases and the recur- rent rate was 11.4% （8/70）. Conclusion： TURBT combining with intravesical mitomycin perfusion is an effective method to treat non- invasive bladder urothelial carcinoma with few complicatons.

关 键 词：经尿道电切术 丝裂霉素 膀胱癌 

分 类 号：R737.14[医药卫生—肿瘤] R730.58[医药卫生—临床医学]