类风湿关节炎寒湿痹阻证用药规律研究  

Research on the Compatibility Laws in Treating Rheumatoid Arthritis Patients of Cold-dampness Obstruction Syndrome

作　　者：柳春[1] 梁永林[2] 姚柳伊[3] 

机构地区：[1]甘肃中医学院公共课部计算机教研室,兰州730000 [2]甘肃中医学院基础课部,兰州730000 [3]甘肃中医学院中医系,兰州730000

出　　处：《中国中西医结合杂志》2013年第9期1269-1272,共4页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：甘肃省卫生厅中医药科研项目(No.GZK-2012-73);甘肃中医学院中青年基金项目(No.06ZQ-10)

摘　　要：目的通过对临床运用中药复方治疗类风湿关节炎寒湿痹阻证文献的归纳性回顾,探讨其治疗的高频药物,以期提高中医药方药理论与医疗实践水平。方法选取近30年医学期刊治疗类风湿关节炎寒湿痹阻证的中药复方,建立中药复方数据库,对用药的功效、归经、性味等特征进行统计。结果治疗类风湿关节炎寒湿痹阻证的75首复方中单味药126味,前31味药累积使用频次占总频次的70.7%,是治疗类风湿关节炎寒湿痹阻证的高频药物。从功效分类看,祛风湿药、补虚药、解表药和活血化瘀药是治疗类风湿关节炎寒湿痹阻证的高频药物。从药物归经看,肝、脾、肾经药居前3位。药味以辛、苦、甘为主。药性以温性药使用最多。结论分析统计得到的高频药物,为临床选择用药提供依据。Objective To find out Chinese herbal compounds （CHCs） with high frequency in trea- ting rheumatoid arthritis （RA） patients of cold-dampness obstruction syndrome （CDOS） by inductively re- viewing literatures concerning clinical application of CHCs, thus improving theoretical and medical practice levels of Chinese medical recipes. Methods The CHCs for treating RA patients of CDOS published in med- ical journals in recent 30 years were retrieved. The database of CHCs was set up. The herbal functions, me- ridian tropism, flavors and properties were statistically analyzed. Results There were 126 single herbs in CHCs for treating RA patients of CDOS. The top 31 single herbs occupied 70.7% cumulative frequency, be- ing high frequency CHCs for treating RA patients of CDOS. From the function aspect, the anti-rheumatic herbs, asthenia supplementing herbs, diaphoretics, and herbs for activating blood circulation and remo- ving blood stasis were identified as high frequency CHCs. From the meridian tropism aspect, Gan-meridi- an, Pi-meridian and Shen-meridian,occupied the top 3. As for flavors, acrid, bitter, and sweet occupied the top three. As for drug nature, herbs of warm property were used most frequently. Conclusion The high frequency CHCs obtained from analytical statistics could provide evidence for clinical medication.

关 键 词：类风湿关节炎 寒湿痹阻证 中药复方 用药规律 

分 类 号：R259[医药卫生—中西医结合]