生长抑素治疗肝性胸水的价值  

The value of somatostatin in the treatment of hepatic hydrothorax

作　　者：许亮[1] 韩炎炎[1] 刘敏[1] 

机构地区：[1]苏州大学附属第二医院高新区医院消化科,江苏苏州215000

出　　处：《胃肠病学和肝病学杂志》2013年第9期933-935,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨生长抑素对肝性胸水的治疗价值。方法收集54例肝性胸水患者进行回顾性分析,总结其临床特点。随机分成治疗组和对照组,治疗组采用生长抑素治疗。观察两组治疗后临床症状及胸水的改善情况,同时观察在治疗过程中两组并发症的情况。结果肝性胸水男性多见,乙肝后肝硬化为主要病因,胸水以右侧为主。经治疗后治疗组总有效率达86.2%,明显高于对照组(68.0%,P<0.05)。治疗过程中治疗组并发症总发生率为34.5%,明显低于对照组(60.0%,P<0.01),并发症中以水电解质紊乱最为常见。结论生长抑素能有效治疗肝性胸水并减少并发症的发生。Objective To explore the value of somatostatin in the treatment of hepatic hydrothorax. Methods 54 patients with hepatic hydrothorax were randomly divided into two groups： somatostatin treatment group and control group. All the clinical features were summarized. The difference was compared between two groups including the clinical efficacy, the reduction of hydrothorax and side effects. Results The male was easier to appear hepatic hydrothorax. The liver cirrhosis after HBV was the main pathogen and the dominant place happened in the right thorax. The total effective rate in the treatment group was much higher than that in the control group （86.2% vs 68.0% ） , which had statistical difference （P 〈 0.05）. Meanwhile, the total rate of side effects in the treatment group was much lower than that in the control group （34.5% vs 60.0% ） , which had statistical difference （P 〈 0.05）. And electrolyte disturbance was the main side effect. Conclusion Somatostatin can effectively treat the hepatic hydrothorax and decrease the incidence of side effects.

关 键 词：生长抑素 胸水 肝硬化 治疗 并发症 

分 类 号：R575[医药卫生—消化系统]