微弧氧化和水热处理复合制备钛合金生物涂层及其组织相容性研究  

Preparation of Bio-film on the Surface of Titanium Alloy by Micro-arc Oxidation and Hydro-thermal Synthesis and Its Histocompatibility

作　　者：罗锐[1] 刘忠德[1] 周兴华[2] 程晓农[1] 张迎涛[1] 武文钰[2] 

机构地区：[1]江苏大学材料科学与工程学院,江苏镇江212013 [2]江苏大学食品与生物工程学院,江苏镇江212013

出　　处：《钢铁钒钛》2013年第4期13-18,共6页Iron Steel Vanadium Titanium

基　　金：江苏省自然科学基金资助项目(BK2003051)

摘　　要：采用微弧氧化及水热合成处理方法制备钛合金表面生物膜层。应用扫描电子显微镜,EDS元素能谱及X射线衍射对薄膜的微观形貌、元素成分和相组成进行观察和分析,通过划痕试验检测膜基结合力,并研究试样在Hank’s模拟体液中耐腐蚀性能。将试样高温消毒后,分别植入至动物皮下组织,52 d后取出种植体并进行分析。结果表明:膜层与基体结合力可达26 N左右,MAO-HS试样耐腐蚀性远强于基体试样;试验动物在试验过程中均未发生异常情况,微观形貌分析MAO-HS组试样发现膜层表面存在大量组织攀附,并含有一定比例的C、K元素。对照基体试样组,未见组织攀附。作为种植体材料,较基体合金MAO-HS试样表现出更为优异的组织相容性。Microare oxidation（MAO） and hydrothermal synthesis（HS） technologies were used to prepare biofilm on the surface of titanium alloy. Surface morphologies and formation procedures of the films at vari ous stages were observed by scanning electron microscope, and element and phase compositions of biologi cal membrane layer were analyzed by energy dispersive spectroscopy and Xray diffractometer. The cohe sion between films and substrate materials was measured by scratching test, and the corrosion resistance of samples in Hank＇ s simulated body fluid was probed into. MAOHS samples and titanium alloy substrate samples were implanted into animal subcutaneous tissue after washing and sterilization. After 52 days of im planting, the samples were taken out and observed. The experimental results show that the cohesion be tween the films and substrates has a higher binding force of up to 26 N or so, and the corrosion resistance of MAOHS samples is better than titanium alloy substrate specimen. Large tissues clamber over the surface of MAOHS group , and the membrane layer contains a certain proportion of carbon and kalium element while there is no tissue growth found on the surface of titanium alloy substrates. Compared with the titanium alloy substrate material, MAOHS samples shows more excellent histocompatibility as implants.

关 键 词：钛合金 微弧氧化 水热处理 生物涂层 皮下种植 组织相容性 

分 类 号：TG174.44[金属学及工艺—金属表面处理]