536例乳腺癌的临床病理特征及预后分析  

Breast cancers' clinicopathologic features and prognosis:an analysis of 536 cases

作　　者：王红群[1] 李道旺[2] 吴正升[3] 

机构地区：[1]安徽省合肥市第三人民医院病理科,安徽合肥230022 [2]解放军105医院外科,安徽合肥230031 [3]安徽医科大学病理教研室,安徽合肥230032

出　　处：《安徽医药》2013年第9期1536-1538,共3页Anhui Medical and Pharmaceutical Journal

摘　　要：目的分析乳腺癌的临床病理资料特征及预后。方法回顾复习536例乳腺癌的档案资料,并进行随访。结果乳腺癌主要集中在30～59岁的年龄段(占75.3%),约8.6%的患者有乳腺良性疾病史,214例患者淋巴结无癌转移(占46.2%),ER、PR及CEA阳性率分别为57.3%、60.1%及62.4%,CEA阳性表达与淋巴结转移有关。结论良性乳腺疾病史可能是乳腺癌的病因之一,有淋巴结转移患者、临床分期Ⅲ～Ⅳ期和肿瘤大于5 cm的患者生存率低,ER及PR阳性患者生存率高。Objective To investigate the clinical and pathological features and prognosis of breast cancers. Methods We reviewed the archival data of 536 breast cancers, and conducted follow-up. Results Breast cancers mainly concentrated between 30 - 59 years old （75.3%）. About 8.6% of the cases had the history of mammary gland benign disease,and 214 cases hadn＇t lymph node metastasis （46.2%）. Positive rates of ER,PR and CEA in breast cancers were 57.3% ,60.1% and 62.4% respectively. CEA was correlated with lymph node metastasis in breast cancers. Conclusions Mammary gland benign disease is maybe one of the causes for breast causes. Stage Ⅲ - Ⅳ ,tumor size greater than 5.0 cm and lymph node metastasis was respectively correlated with lower survival rates. Patients of ER and PR positive had higher survival rates.

关 键 词：乳腺癌 生存率 ER PR CEA 预后 

分 类 号：R737.9[医药卫生—肿瘤]