软腭外周T细胞淋巴瘤1例并文献复习  

Peripheral T-cell lymphoma of soft palate:a case report and literature review

作　　者：吴辉菁[1] 于丁[1] 杨业勤[2] 谢蓉[1] 蒋晖[1] 吴月兵[1] 范玉华[1] 

机构地区：[1]湖北省肿瘤医院淋巴瘤内科,武汉430079 [2]枝江市人民医院肿瘤科

出　　处：《临床血液学杂志》2013年第5期652-654,共3页Journal of Clinical Hematology

摘　　要：1病例资料患者，男，46岁，于2009年6月出现左软腭溃疡，约1．5cm×1．0em，边缘清，伴刺痛，影响进食，行抗生素治疗未见缓解。Summary A patient presented to the hospital with recurrent ulcer on the left side of the soft palate. The pathologic diagnosis of biopsy of the soft palate was peripheral T-cell lymphoma, unspecified. PET-CT scan re- vealed mass-like lesion involving palate, oropharynx and nasopharynx, with high-tissue-density and hyperme- tabolism. Bone marrow cytology revealed that lymphoblast count was about 0. 5 ~, serum LDH was 312.4 U/L. The clinical diagnosis was peripheral T-cell lymphoma of the soft palate, non-specified, stage ]~ A, and aaIPI with one score. The patient had a history of chronic hepatitis B. There was no response after the patient received chemo- therapy （including regimens of CHOP and ABVD） and local irradiation treatment. During the treatment, HBV was reactivated. After the patient received GP chemotherapy combined with lamivudine therapy followed by single-a- gent gemcitabine as maintenance treatment,complete response was achieved till now.

关 键 词：软腭 外周T细胞淋巴瘤 乙肝病毒再激活 吉西他滨 

分 类 号：R733.4[医药卫生—肿瘤]