经内镜平行法双金属支架引流治疗晚期肝门部胆管恶性梗阻的疗效评价  

Evalution of double metal stents through the parallel method for treatment of unresectable hilar malignant biliary obstruction

作　　者：王成[1] 黄强[1] 邵峰[1] 胡元国[1] 邱陆军[1] 查恕云[1] 

机构地区：[1]安徽省立医院普外科,合肥230001

出　　处：《肝胆外科杂志》2013年第4期276-279,共4页Journal of Hepatobiliary Surgery

基　　金：安徽省科技厅科技计划项目(项目编号:10021303002)

摘　　要：目的探讨经内镜"平行法"双金属支架引流治疗晚期肝门部胆管恶性梗阻的可行性、安全性及疗效。方法采用对照研究的方法,将2011年1月至2012年12月期间收治的69例经内镜置放不同种类和数量支架进行治疗的晚期肝门部胆管恶性梗阻的临床资料进行总结和分析。结果双金属支架组相对于双塑料及单塑料支架组而言,具有更长的支架平均通畅时间(187±10 d VS.139±8.8 d VS.99±3.3 d;P<0.05)和患者平均生存时间(239±10 d vs 191±8.8 d VS.151±3.3d;P<0.05),但三组之间的减黄效果和术后并发症的发生率无统计学差异。结论采用经内镜"平行法"双金属支架引流治疗晚期肝门部胆管恶性梗阻是安全、可行的。其在支架平均通畅时间和病人平均生存时间方面均明显优于塑料支架。Objective To compare the effects and safety of double metal endoscopic biliary stents placement by the parallel method with plastic stent on unresectable malignant biliary obstruction. Methods The clinical data of 69 patients with obstructive jaun- dice due to advanced carcinoma who were treated with bifiary plastic stent or metal stents from January 20ll to December 2012 were retrospectively analyzed. Results Compare with double or single plastic stent, the double endoscopic biliary stents placement by the parallel method has longer stent patency（ 187 ± 10 d vs 139± 8. 8 d;99 ± 3.3 d;P 〈 0. 05 ）. Moreover, the double metal endoscopic biliary stents placement has longer survival（ 239 ± 10 d vs 191± 8, 8 d, 151 ±3.3 d;P 〈 0. 05）. The rate of complication is no signifi- cant among three groups. Conclusion Compare with double or single plastic stent, the double metal endoscopic biliary steuts place- ment by the parallel method could effectively extinct jaundice for patients with unresectable biliary obstruction caused by malignant neo- plasm and improved the life quality.

关 键 词：肝门部胆管 恶性梗阻 内镜诊治 平行法 双金属支架引流 

分 类 号：R735.8[医药卫生—肿瘤]