腹腔镜结直肠癌根治术患者围术期血清肿瘤标志物水平变化的观察  

Observation on the change of serum tumor markers of patients with laparoscopic resection of colorectal cancer during perioperative period

作　　者：邓长辉[1] 谢明[1] 

机构地区：[1]长沙市中心医院,长沙410000

出　　处：《中国当代医药》2013年第27期21-22,共2页China Modern Medicine

摘　　要：目的观察研究腹腔镜结直肠癌根治术患者围术期血清肿瘤标志物水平的变化规律。方法选取2010年7月～2013年4月于本院进行腹腔镜结直肠癌根治术治疗的36例患者为观察组,并将同时期进行体检且检查示健康的36名人员设为对照组,将观察组术前1 d和术后3、7、10 d及对照组的血清CA242、CEA、CA724及CA199的含量与阳性率进行比较。结果观察组术前1 d及术后3 d、7 d血清CA242、CEA、CA724及CA199含量与阳性率均高于对照组(P<0.05),而术后10 d的4个指标的含量与阳性率与对照组差异无统计学意义(P>0.05)。结论腹腔镜结直肠癌根治术患者围术期血清肿瘤标志物水平呈现持续下降的趋势,可有效反应疾病的治疗效果。Objective To observe and study the variation of serum tumor markers of patients with laparoscopic resec- tion of colorectal cancer during perioperative period. Methods 36 patients with laparoscopic resection of coorectal cancer in our hospital from July 2010 to April 2013 were selected as observation group,36 healthy personal with phys- ical examination at the same period were the control group,then the content and positive rate of serum CA242,CEA, CA724 and CA199 of observation group at first day before the operation and at third, seventh and tenth day after the operation and control group were compared. Results The content and positive rate of serum CA242,CEA, CA724 and CA199 of observation group at first day before the operation and at third,seventh day after the operation were all higher than those of control group （P〈0.05）,while the content and positive rate of four indexes at tenth day after the operation had no significant differences to those of control group （P〉0.05）. Conclusion The serum tumor markers of patients with laparoscopic resection of colorectal cancer during perioperative period shows a continued downward trend,and it can effectively reflect the treatment effect of disease.

关 键 词：腹腔镜结直肠癌根治术 围术期 血清肿瘤标志物 变化规律 

分 类 号：R735.37[医药卫生—肿瘤]