硒对胃癌化疗敏感性影响的研究进展  

Advances in Effects of Selenium Against Chemotherapeutic Sensitivity for Gastric Cancer

作　　者：陈晋[1] 陈家强[1] 罗斌[1] 王建洲[1] 刘长俊[1] 章顺悦[1] 

机构地区：[1]湖北医药学院,湖北十堰442000

出　　处：《预防医学情报杂志》2013年第8期719-722,共4页Journal of Preventive Medicine Information

摘　　要：胃癌因在我国各类恶性肿瘤中的高发病率及高死亡率而倍受关注。由于胃癌单纯的手术治愈率不高,且易出现复发或转移,因此,化疗是其主要的治疗手段之一。但化疗的不良反应太大,致使很多患者不能完成治疗。硒是人体所必需的营养元素,同时也是一种广泛的抗癌因子,目前人们对硒的研究,主要侧重于作为癌症化疗辅助剂的作用,硒能明显降低化疗药物的不良反应,并且在协同化疗药物抗肿瘤方向发挥着重要的作用。An increasing attention is paid to gastric cancer in China for its high incidence and mortality rates. Chemotherapy is one of the main treatments due to the comparatively low cure surgery rate as well as easy relapse and transfer. Nevertheless, many patients can not accomplish the treatment for reason of adverse reaction of chemotherapy. With wide effects, the selenium is necessary for the body. The current researches about selenium mainly focus on agent - assisted in cancer chemotherapy, while selenium can significantly reduce the adverse reactions of chemotherapy, thus plays an important role against tumor collaborate with chemotherapy drugs.

关 键 词：胃癌 硒 化疗 抗癌机制 

分 类 号：R735.2[医药卫生—肿瘤]