金丝桃苷在刺五加各部位中的分布及其对胰脂肪酶活性的抑制作用  

Distribution and Inhibitory Activity on Pancreatic Lipase of Hyperin in Acanthopanax senticosus

作　　者：刘芳芳[1,2] 张晶[2] 张传奇[2] 薛起 郑毅男[2] 张连学[2] 

机构地区：[1]长春科技学院,长春130600 [2]吉林农业大学中药材学院,长春130118 [3]吉林修正生物工程有限公司,长春130600

出　　处：《吉林农业大学学报》2013年第4期442-445,共4页Journal of Jilin Agricultural University

基　　金：吉林省教育厅"十一五"科学技术研究项目[吉教科合字(2009)第579号]

摘　　要：采用高效液相色谱法测定了刺五加根、茎干、新枝、茎皮、茎韧皮部、叶、花蕾、果中金丝桃苷的含量,并研究了金丝桃苷体外抑制胰脂肪酶的活性。结果表明:刺五加花蕾中金丝桃苷含量最高,达2.4%,金丝桃苷对胰脂肪酶活性有一定的抑制作用,质量浓度为1 mg/mL时抑制率为24.852%。The content of hyperin in root,shoot,new branch,skin of shoot,phloem of shoot,leaf,flower and fruit was determined with HPLC and the activity of pancreatic lipase on hyperin was studied.The results showed that the content of hyperin was the highest in flower,2.4%.At the concentration of 1 mg/mL,hyperin inhibited the activity of panvreatic lipase by 24.852%.

关 键 词：刺五加 金丝桃苷 含量 胰脂肪酶 活性 抑制作用 

分 类 号：R284.1[医药卫生—中药学] R285.5[医药卫生—中医学]