藏药木橘挥发油化学成分气相色谱-质谱联用分析  

GC- MS Analysis of Chemical Constituents in Volatile Oils from Tibetan Medicine Aegle marmelos(L. ) Correa

作　　者：武尉杰[1] 谭睿[1] 卢琼[1] 谢彬[1] 

机构地区：[1]西南交通大学生命科学与工程学院,四川成都610031

出　　处：《中国药业》2013年第17期11-13,共3页China Pharmaceuticals

基　　金：科技部科技基础性工作专项项目;项目编号:2009FY220100;2011年自然科学基金面上项目;项目编号:81173594;中央高校基本科研业务费专项资金项目;项目编号:SWJTU11ZT26

摘　　要：目的促进藏药木橘的开发利用。方法采用水蒸气蒸馏法提取挥发油,峰面积归一化法测定相对含量,气相色谱-质谱联用技术(GC-MS)辅助人工检索鉴定其化学成分。结果共分离和鉴定了33个化合物,占挥发油总量的91.82%,其中脂肪酸类相对百分含量为51.97%。藏药木橘挥发油的主要成分为棕榈酸(40.04%),β-石竹烯(10.04%),油酸(7.83%),香叶烯B(5.33%),α-葎草烯(3.53%),γ-姜黄烯(2.61%)和α-桉叶烯(2.30%)等。结论藏药木橘具有较好的药物开发潜质,值得深入研究。Objective To promote the development and utilization of Tibetan medicine Aegle marmelos （L.） Correa. Methods The water steam distillation method was adopted to extract the volatile oils from Aegle marmelos （L.） Correa. The relative amount of each constituent was determined by the peak area normalization method. The chemical constituents were separated and identified by GC- MS assisted the manual retrieval. Results Thirty-three chemical compounds were separated and identified, accounting for 91.82% of the total volatile oils,in which the relative percentage composition of fatty acids was 51.97%. The main components of Tibetan medicine Aegle marmelos （L.） volatile oil are hexadecanoic acid （40.04%）, beta - caryophyllene（ 10.04% ）, 9 - octadecenoic acid （7.83%）, germacrene B（5.33% ）, alpha-humulene（3.53% ）, gamma-curcumene（2. 61% ） and alpha-selinene（2. 30% ）. Conclusion Tibetan medicine Aegle marmelos （L.） has better medicinal development potential and deserves to be deeply researched

关 键 词：木橘 挥发油 气相色谱-质谱联用 

分 类 号：R284.1[医药卫生—中药学] R282.71[医药卫生—中医学]