非酒精性脂肪性肝病与氧化应激  

Non-alcoholic fatty liver disease and oxidative stress

作　　者：张艳[1] 卢洁[1] 周莹群[1] 徐凌[1] 郭传勇[1] 

机构地区：[1]同济大学附属第十人民医院消化科,上海200072

出　　处：《世界临床药物》2013年第8期459-463,共5页World Clinical Drug

基　　金：国家自然科学基金资助项目(81270515);上海市科委重点课题(11430702400);中国肝炎防治基金会肝病研究基金资助项目(20100021;20120005);上海市卫生局课题(2011287;2012107)

摘　　要：非酒精性脂肪性肝病常与肥胖、2型糖尿病和高血压等代谢综合征并存,其与氧化应激的关系越来越受到关注。本文综述非酒精性脂肪性肝病的发病机制、氧化应激及其相关抗氧化剂的研究。Non-alcoholic fatty liver disease always coexists with obesity, type 2 diabetes, hypertension and other metabolic syndrome. The correlation between non-alcoholic fatty liver disease and oxidative stress are more concerned in recent years. This review summarizes the pathogenesis of non-alcoholic fatty liver disease and the development on oxidative stress and antioxidants.

关 键 词：非酒精性脂肪性肝病 氧化应激 抗氧化剂 

分 类 号：R575.5[医药卫生—消化系统] R975[医药卫生—内科学]