吴茱萸挥发油的包合工艺优化  

Optimization on Inclusion Technology of Volatile Oil from Evodia rutaecarpa

作　　者：覃海龙[1] 王安辉[1] 杨碧仙[2] 云雪林[1] 

机构地区：[1]贵阳中医学院药学院,贵州贵阳550002 [2]贵阳学院食品与制药工程学院,贵州贵阳550005

出　　处：《贵州农业科学》2013年第8期166-169,共4页Guizhou Agricultural Sciences

基　　金：贵州省教育厅自然科学研究项目重点课题"萸姜药效组分方剂配伍研究"[黔教科(2010)048];国家重点基础研究发展计划(973)子课题"辛热药物与温通心阳药效的相关性研究"[2007CB212606];贵州省中药现代化专项项目"吴茱萸优质道地药材评价体系构建"[黔科合ZY(2011)3010]

摘　　要：为提高吴茱萸挥发油的稳定性,保证组分的药效,对超临界CO2萃取的黔产吴茱萸挥发油进行超声法β-环糊精包合工艺的最佳条件优选研究。采用正交试验设计,考察包合温度、β-环糊精与挥发油比例、包合时间等因素对包合工艺的影响,以包合物得率和挥发油包合率为指标,优选吴茱萸挥发油的β-环糊精包合工艺。结果表明:超声法,包合温度40℃,β-环糊精与挥发油比例8∶1,饱和时间2h为最佳包合条件,包合物得率为61.54%,包合率为74.25%。In order to improve stability of the volatile oil from E.rutaecarpa,and ensure the component efficacy,optimal selection of the best conditions of the ultrasound method β-cyclodextrin inclusion process of volatile oil form E.rutaecarpa in Guizhou was conducted by supercritical CO2 extraction.By using orthogonal design method,the authors took the effects of inclusion temperature,proportion of β-cyclodextrin and volatile oil,including time,yield of inclusion and the utilization rate of volatile oil as indexes,to optimize the inclusion process.The results showed that the optimal inclusion condition by ultrasonic method were inclusion temperature 40℃,β-cyclodextrin-volatile oil ratio 8 ∶ 1,inclusion time 2 h,the yield of inclusion complexes was 61.54% with the inclusion rate of 74.25%.

关 键 词：黔产吴茱萸 超临界 挥发油 超声法 包合 

分 类 号：S377[农业科学—农产品加工]