特异针刺和非甾体抗炎药对兔急性骨骼肌损伤疼痛的影响  

Effect of special acupuncture therapy and /or NSAIDS on the pain of rabbits suffering from acute skeleton muscle injury

作　　者：刘霞[1] 郭勇力[2] 

机构地区：[1]山东体育学院体育运动学校,山东济南250102 [2]山东体育学院,山东济南250102

出　　处：《山东体育学院学报》2013年第4期52-54,共3页Journal of Shandong Sport University

基　　金：山东省自然科学项目(Y2003C01)

摘　　要：目的:探讨特异针刺和非甾体抗炎药两种治疗方法对兔急性骨骼肌损伤后疼痛的影响。方法:采用随机对照原则,将急性骨骼肌损伤造模成功的24只新西兰白兔分成4组:针刺组、给药组、针刺+给药组和对照组。用酶联免疫法测不同时刻(损伤前、损伤后即刻、损伤后第1、2、3、6天)兔血清前列腺素E2(PGE2)的浓度来检验不同治疗方法对兔急性骨骼肌损伤疼痛的影响。结果:与对照组相比,在损伤后第一天三个治疗组血清PGE2值均显著性的降低(P<0.05);针刺+给药组有非常显著性效果(P<0.01),三种疗法相互间比较无显著性差异(P>0.05)。在损伤后第二天,各组血清PGE2显著性降低(P<0.05);非甾体抗炎药组和针刺+给药组血清PGE2与对照组有非常显著性的差异(P<0.01);三种疗法比较无显著性差异(P>0.05)。在损伤后第三天特异针刺治疗组血清PGE2的值与对照组比无明显差异(P>0.05),非甾体抗炎药治疗组和针刺+给药组血清PGE2的值与对照组相比有显著性差异(P<0.05);三种疗法相互比较无显著性差异(P>0.05)。结论:特异针刺和非甾体抗炎药均可降低兔急性骨骼肌损伤后的疼痛程度,两者具有相同疗效;两种疗法联合应用有优于两种疗法单用的趋势。Objective： Special acupuncture therapies and / or NSAIDs were used on rabbits suffering from acute skeleton muscle injury, to verify which treatment is better in relieving the pain in acute skeletal muscle injury. Methods ： 24 New Zealand white rabbits suffering from acute skeleton muscle injury are randomly divided into 4 groups, 6 in each group. A ： acupuncture group , B ： drug group, C： acupuncture ＋ drug group, D： control group. Collect arterial blood sample before feeding them in the morning, to detect the concentration of PGE2 in serum of rabbits by enzyme - linked immu-nosorbent assay at different times （before the injury, immediately after injury, the 1,2,3,6 days af-ter injury） to verify which treatment is better to induce the pain in acute skeletal muscle injury. Re-sults ： Compared with the control group, in the first day after injury, the concentration of PGE： in se-rum of three treatment groups decreased （ P 〈 0.05 ）, decreased significantly in the acupuncture ＋ drug group （ P 〈 0.01 ）, but no significant difference among the three groups （ P 〉 0.05 ） ; In the sec-ond day, the concentration of PGE2 in serum of three treatment groups decreased （ P 〈 0.05 ）, there being significant difference between the drug group and acupuncture ＋ drug group （P 〈 0.0! ）, but no significant difference among the three groups（ P 〉 0.05 ） ; In the third day, the concentration of PGE2 in serum of the drug group and acupuncture ＋ drug group decreased （ P 〈 0.05 ） , no signifi-cant change in acupuncture group （ P 〉 0.05 ） ; but no significant difference among the three groups （ P 〉 0.05 ） ; the sixth day, the concentration of PGE2 inserum of groups are not significantly different （ P 〉 0. 05 ）. Conclusions ： The special acupuncture therapy and the NSAIDs therapy may relieve the pain in rabbits suffering from acute skeleton muscle injury, and combination of two methods ends to be better than using only one.

关 键 词：急性骨骼肌损伤 PGE2 特异针刺 非甾体抗炎药 

分 类 号：G804.5[文化科学—运动人体科学]