超声造影在子宫肌瘤射频消融治疗中的应用  

Application of Contrast-enhanced Ultrasound in Treatment of Uterine Myoma with Radiofrequency Ablation

作　　者：甘玲[1] 叶真[1] 郑秀[2] 陈秀清[2] 黄秀烟[1] 

机构地区：[1]福建医科大学 附属第一医院超声影像科,福州350005 [2]福建医科大学 附属第一医院妇产科,福州350005

出　　处：《福建医科大学学报》2013年第3期184-186,共3页Journal of Fujian Medical University

基　　金：福建省卫生厅青年科研课题(2007-2-30)

摘　　要：目的探讨灰阶超声造影(CEUS)在子宫肌瘤自凝刀射频消融治疗中的应用价值。方法超声导向经阴道自凝刀射频消融(RFA)治疗前分别对59例已育妇女71个子宫肌瘤(其中肌壁间肌瘤22个,黏膜下肌瘤49个)行常规超声及CEUS检查,RFA治疗后即刻行CEUS检查来评判消融效果,部分带蒂黏膜下肌瘤消融后随即取出送病理。治疗后于3,6,12月常规超声观察肌瘤体积变化、血供及患者临床症状改善情况。结果术前行CEUS检查71个病灶均符合子宫肌瘤"周边网状增强型"的造影增强模式;RFA术后即刻病灶CEUS表现为"缺损型"造影增强模式。RFA术后3,6,12月肌瘤平均体积明显缩小,差别有统计学意义。结论 RFA术前、术后即刻CEUS的应用,严格掌握手术适应症有助于提高RFA治疗子宫肌瘤的疗效。Objective To explore the clinical value of contrast-enhanced ultrasound(CEUS) in the treatment of uterine myoma with radiofrequency ablation (RFA ) . Methods 59 patients with 71 uterine myoma (22 intramural fibroids and 49 submucosal fibroids) were examinated by routine ultrasound and CEUS before RFA . CEUS was performed immediately after the RFA treatment to assess the efficacy , and partially pedunculated submucosal fibroids were removed and sent for pathological analysis right after the ablation . 3 ,6 and 12 months after the treatment ,the volumes and blood flow s of the fibroids and changes of clinical symptom were evaluated . Results The enhancement patterns of all tumors were pe-ripheral net pattern ,while after RFA lesions were un-enhanced with CEUS . 3 ,6 and 12 months after the RFA treatment ,the average volumes of fibroids significantly became smaller ,and the difference was of statistic significance . Conclusion CEUS applicated preoperatively and postoperatively can improve the efficacy in the treatment of uterine myoma with RFA .

关 键 词：导管消融术 平滑肌瘤 生殖器 肿瘤 子宫肿瘤 超声检查 造影剂 

分 类 号：R737.33[医药卫生—肿瘤]