膀胱癌3.0T MRI多b值弥散加权成像研究  

A study of multi-b values diffusion weighted imaging of bladder cancer at 3.0T MRI

作　　者：范瑜[1] 刘晓晟[1] 路青[1] 姚秋英[1] 

机构地区：[1]上海交通大学医学院附属仁济医院放射科,上海200001

出　　处：《诊断学理论与实践》2013年第3期334-338,共5页Journal of Diagnostics Concepts & Practice

基　　金：上海市重点学科(S30203);上海交通大学医学院重点学科

摘　　要：目的:回顾性分析3.0 T MRI膀胱癌不同b值的弥散加权成像(DWI)表现和表观弥散系数(ADC),探讨高场强MRI最佳b值的选取。方法:对30例经病理证实为膀胱癌的患者进行MRI常规成像及DWI检查。梯度扩散因子b值分别取700 s/mm2、1 000 s/mm2和1 500 s/mm2。观察膀胱癌不同b值的DWI表现,测量肿瘤信噪比(SNRC)、肿瘤对正常膀胱壁和尿液的对比信噪比(CNRCB、CNRCU)及测量不同b值时肿瘤的ADC值,并进行统计分析。结果:DWI可显示所有肿瘤病灶,呈偏高信号肿块影;随着b值增加,肿瘤SNRC下降,而CNRCB、CNRCU升高,差异有统计学意义(P<0.05);随着b值增加,肿瘤平均ADC值虽有减小趋势,但差异尚无统计学意义(F=3.04,P>0.05)。结论:当b值取1 500 s/mm2时,在不影响病灶显示的情况下可获得较高的对比信噪比和相对准确的ADC值,有助于膀胱癌的早期发现和准确分期。Objective To study the diffusion weighted imaging(DWI) and the apparent diffusion coefficient(ADC) value of bladder cancer with different b values,and to determine the optimal b value of bladder cancer at 3.0 T MRI.Methods Thirty patients with proven bladder cancer were scanned with conventional MRI and DWI.B values were set as 700 s/mm2,1 000 s/mm2,and 1 500 s/mm2,respectively.The DWI appearances were analyzed;SNRC,CNRCB,CNRCU and ADCs were calculated under different b values.Results All the bladder cancer showed high signal intensity in DWI.With the increase of b value,SNRC decreased and CNRCB,CNRCU increased(P<0.05).No significant difference of mean ADC value in bladder cancer was observed under different b values(F=3.04,P>0.05).Conclusions 1 500 s/mm2 is the optimal b value for DWI of bladder cancer at 3.0T MRI.Bladder cancer shows higher CNR on DWI,which could help the early diagnosis with accurate staging.

关 键 词：膀胱癌 磁共振成像 弥散加权成像 表观弥散系数 

分 类 号：R737.14[医药卫生—肿瘤]