棕榈花蕾水提物抗雌性小鼠生育作用  

The effect of aqueous extract of kittul alabastrum on antifertility in female mice

作　　者：齐汝霞[1,2] 张鹏[2] 姚晓红[3] 王传功[2] 李卫平[1] 

机构地区：[1]安徽医科大学基础学院,安徽合肥230032 [2]济宁医学院基础学院,山东济宁272067 [3]济宁医学院附属济宁市第一人民医院,济宁272011

出　　处：《济宁医学院学报》2013年第4期253-255,共3页Journal of Jining Medical University

摘　　要：目的探讨棕榈花蕾水提物对雌性小鼠的抗着床、抗早孕及避孕作用。方法给雌性小鼠分别用低剂量(2.5g/kg)、中剂量(5g/kg)和高剂量(10g/kg)的棕榈花蕾水提物灌胃,研究其抗着床、抗早孕及避孕作用。结果抗着床实验中低、中、高剂量棕榈花蕾水提物对小鼠的妊娠抑制率为60%以上,中高剂量棕榈花蕾水提物对早期妊娠小鼠有明显致流产作用。中、高剂量棕榈花蕾水提物能使小鼠的避孕率达100%。结论棕榈花蕾水提物具有显著的抗着床、抗早孕及避孕作用。Objective To explore anti-implantation, anti-early pregnancy function and contraceptive effect of aqueous extract of kittul alabastrum in mice. Methods To study the effect of anti-implantation, anti-early pregnancy function and contraceptive effect of mice which were given aqueous extract of kittul alabastrum with 2.5 g/ kg, 5 g/kg, 10g/kg. Results In the experiment of anti-implantation, inhibition rate of pregnancy was over 60 %, and middle and high dose group induced miscarriage of early pregnancy mice. Contraception rate of middle dose and high dose group was 100%. Conclusion Aqueous extract of kittul alabastrum was anti-implantation, anti-early pregnancy and contraceptive effect on female mice.

关 键 词：棕榈花蕾水提物 雌性小鼠 抗着床 抗早孕 避孕 

分 类 号：R-33[医药卫生]