跨声门癌喉软骨支架受累的组织病理学观察  

Histopathological study of framework invasion in transglottic carcinoma

作　　者：王雪峰[1] 齐风杰[1] 潘子民[2] 费声重[2] 关超[2] 

机构地区：[1]锦州医学院附属第一医院耳鼻咽喉-头颈外科,辽宁锦州121001 [2]中国医科大学附属第一医院耳鼻咽喉科,辽宁沈阳110001

出　　处：《中国耳鼻咽喉颅底外科杂志》2000年第4期200-202,I002,共4页Chinese Journal of Otorhinolaryngology-skull Base Surgery

摘　　要：目的　探讨跨声门癌喉软骨支架受累的特点及意义。方法　选择临床喉全切除标本 50例 ,火棉胶包埋 ,连续切片观察。结果　跨声门癌喉软骨支架受累为 64% ( 32 / 50 ) ,其中单纯甲状软骨受累为 34 % ( 17/ 50 ) ,甲状软骨和环状软骨同时受累为 30 % ( 15/ 50 ) ;肿瘤早期就可浸润喉软骨支架 ;跨声门癌颈淋巴结转移率为 4 4 % ( 2 2 / 50 ) ,侵及与未侵及喉软骨支架者转移率分别为 56.2 5% ( 18/ 32 )、2 2 .2 2 % ( 4 / 18) ,二者差异显著 ( χ2 =4 .12 ,P <0 .0 5)。结论　充分认识跨声门癌喉软骨支架受累对临床诊断治疗具有重要指导意义。Objective To explore the characteristics and significance of cartilage invasion in transglottic carcinoma. Methods Fifty cases of transglottic carcinoma were chosen and the collodin-embedded specimens of the whole-organ serial section were observed. Results (1)The invasion rate of the cartilage in tansglottic carcinoma was 64% (32/50); the invasion rate of the thyroid and that of the thyroid and cricoid were 34% (17/50) and 30%(15/50) respectively; (2)the cartilage was invaded in the early stage; (3)the metastatic rate of the cervical lymph node was 44%(22/50) in transglottic carcinoma; it was 56.25% (18/32) in cartilage invaded cases, and 22.22% (4/18) in non-cartilage invaded cases; there was remarkable difference (P< 0.05 ).Conclusion Sufficient recognition of cartilage invasion is important in the diagnosis and treatment of transglottic carcinoma.

关 键 词：跨声门癌 喉软骨支架受累 肿瘤转移 组织病理学 

分 类 号：R739.65[医药卫生—肿瘤] R73－37[医药卫生—临床医学]