转移癌脊髓压迫症的短程放射治疗  

Short－course Radiotherapy for Metastatic Spinal Cord Compression

作　　者：向东华 谢丛华[2] 张弓[2] 周福祥[2] 周云峰[2] 

机构地区：[1]湖北恩施州中心人民医院 [2]湖北医科大学附属第二医院放化疗科，武汉 430071

出　　处：《中国肿瘤临床》2000年第12期915-917,共3页Chinese Journal of Clinical Oncology

摘　　要：目的：评价短程放疗方案对转移癌脊髓压迫症的近期疗效及毒副反应。方法：1991年1月至1999年10月，对43例因转移癌引起的脊髓压迫症行短程放疗400cGy／次×5次／周，总量 20Gy，放疗同时辅以激素加脱水剂以预防放射所致的急性水肿。观察背痛、运动功能及括约肌功能变化情况。结果：43例转移癌脊髓压迫症患者背痛缓解、运动功能改善和括约肌功能恢复有效率分别为 81．4％、72．1％和50．0％。无明显毒副反应。结论：短程放疗治疗转移癌脊髓压迫症，毒副反应轻，是一种合适有效的治疗方案。Objective To evaluate the clinical outcome and toxicity of a short－course regimen of radiotherapy for patients with metastatic spinal cord compression MSCC． Methods From January 1991 to October 1999 forty－three MSCC patients underwent short－course radiotherapy 400cGy／fraction 5 fractions per week for a total dose of 20Gy． Steroids and Mannitol were administered during the radiotherapy． Response was assessed according to back pain motor function and bladder capacity before and after treatment． Results The pain relief was achieved in 81．4％ of patients motor function and bladder capacity amelioration rates were 72．1％ and 50．0％ respectively． The toxicity was few． Conclusion Short－course radiotherapy is a convenient and effective regimen for MSCC．

关 键 词：转移癌脊髓压迫症 短程放射治疗 毒副反应 

分 类 号：R730.5[医药卫生—肿瘤]