THP-Lp乳化剂为主介入化疗栓塞治疗肝癌的临床研究  

Clinical Study of Intervening Chemoemobolization with THP－Lp Emulsifier in Treating Liver Neoplasms

作　　者：王庆良[1] 李彩霞[1] 孟红 

机构地区：[1]山东医科大学附属医院放射科导管室,济南市250012

出　　处：《中国肿瘤临床》2000年第12期920-922,共3页Chinese Journal of Clinical Oncology

摘　　要：目的：评价以THP－Lp乳化剂进行栓塞的联合化疗治疗肝癌的临床价值。方法：对119例肝癌患者进行了520例次栓塞化疗治疗，其中单纯碘油（Lp）栓塞214例次，碘油与明胶海绵（GF）联合栓塞109例次，经化疗泵栓塞化疗171例次，经动脉栓塞与经皮肝穿刺联合化疗栓塞26例次。结果：本组患者总有效率（CR＋PR）为74．8％，肝肿瘤缩小50％以上者占50％。4种治疗的有效率有显著差异（χ2检验P＜ 0．05），而肿瘤大小改变无明显差异（P ＞0．05）。结论：以THP－Lp乳化剂为主的联合化疗栓塞应作为肝癌治疗的首选方法，对于乏血型肝癌应采取多种方法联合治疗。Objective To evaluate the value of chemoembolization with THP－Lp emulsifier in treating liver neoplasms． Methods One hundred and nineteen patients were treated 520 person－times of chemoembolization including 1 Only chemoembolizing was 214 person－times 2 chemoembolizing with GF embolization 109 person－times 3 chemoembolizing and／or GF embolization with percutaneous treatment 26 person－times and 4 Through dump 171 person－times． Results The overall response rate CR＋PR was 74．8％ while patients with tumor half shrinkaged accounted for 50％． There existed significant difference χ2 test P＜ 0．05 among the four methods in total response but there was no significant difference P ＞0．05 among them in tumor shrinkage． Conclusion Chemoembolization with THP－Lp emulsifier in treating liver neoplasms should be the first choice． As to those tumors lacking of blood supply two or more methods combined each other might get an ideal effectiveness．

关 键 词：吡柔比星-乙碘油乳化剂 肝癌 化疗栓塞 

分 类 号：R735.7[医药卫生—肿瘤] R730.53[医药卫生—临床医学]