门静脉海绵样变临床特点及病因分析  

Clinical characters and etiology of cavernous transformation of portal vein

作　　者：杨齐[1] 詹雅诗[1] 黄晓丽[1] 柯比伦[1] 杨逸冬[1] 刘慧玲[1] 吴斌[1] 

机构地区：[1]中山大学第三附属医院消化内科,广州510630

出　　处：《中华消化病与影像杂志（电子版）》2013年第3期8-11,共4页Chinese Journal of Digestion and Medical Imageology(Electronic Edition)

摘　　要：目的分析门静脉海绵样变的临床特点与病因。方法收集2006年6月至2010年5月中山大学第三附属医院诊断为门静脉海绵样变的住院患者的临床资料,分析其临床特点并着重对其合并疾病进行回顾性分析。结果共83例患者纳入研究。患者主要因腹痛、上消化道出血入院,临床有门脉高压及相应原发病表现,入院后多次彩色多普勒超声及CT/MRI检查后确诊为门静脉海绵样变。在83例患者中,合并肝硬化者60例,肝癌48例,腹部手术史者24例,肝动脉-门静脉瘘15例,糖尿病8例,布加综合征2例、胰腺癌2例。结论门脉高压并上消化道出血是门静脉海绵样变的主要临床特点;肝硬化及肝癌是门静脉海绵样变的重要病因,肝动脉-门静脉瘘及糖尿病可能是引起门静脉海绵样变的潜在病因。Objective To analyze the clinical characters of cavernous transformation of portal vein （CTPV） and its potential causes. Methods Clinical data of patients diagnosed as CTPV and treated in our hospital from June of 2006 to May of 2010 were collected. The clinical characters and comorbidities of CTPV were analyzed retrospectively. Results Eighty-three patients were enrolled in this research. The main symptoms of these patients were abdominal pain, upper gastrointestinal hemorrhage and the clinical manifestation caused by portal hypertension and the corresponding original diseases. The diagnosis of CTPV was confirmed according to more than once examination of color doppler sonography and CT/MRL Among these 83 patients, complications included cirrhosis （60 cases）, hepatocarcinoma （48 cases）, history of abdominal surgery （24 cases）, hepatic artery-portal vein fistula （HA-PVF, 15 cases）, diabetes （8 cases）, Budd-Chiari syndrome and pancreatic carcinoma （2 cases for each ）. Conclusions Portal hypertension comphcated with upper gastrointestinal hemorrhage is the main chnical character of CTPV; cirrhosis and hepatocarcinoma are the main causes of CTPV, while HA-PVF and diabetes may be its potential causes.

关 键 词：门静脉海绵样变 肝硬化 肝肿瘤 肝动脉-门静脉瘘 糖尿病 

分 类 号：R575[医药卫生—消化系统]