板层角膜移植术联合前房注药治疗真菌性角膜溃疡  

Lamellar keratoplasty combined with anterior chamber injections in the treatment of fungal corneal ulcer

作　　者：张婧[1] 王万鹏[1] 张文芳[2] 鲁建华[2] 

机构地区：[1]兰州大学第二临床医学院,中国甘肃省兰州市730000 [2]兰州大学第二医院眼科中心,中国甘肃省兰州市730000

出　　处：《国际眼科杂志》2013年第10期2025-2027,共3页International Eye Science

摘　　要：目的：总结板层角膜移植术联合前房注药治疗真菌性角膜溃疡的效果。方法：对照组：临床上确诊为真菌性角膜溃疡并行板层角膜移植术的患者;试验组：行板层角膜移植术,并于术中,术后第3,10d前房注入氟康唑0.1mL（0.05mL2g/L氟康唑＋0.05mL生理盐水）的真菌性角膜溃疡患者。结果：随访观察3～6mo,对照组复发率11%,试验组均未见复发。结论：板层角膜移植术联合前房注药是治疗真菌性角膜溃疡的有效方法,并可有效降低术后复发率。AIM： To evaluate the clinical efficacy of lamellar keratoplasty combined with anterior chamber injections in the treatment of fungal corneal ulcer. METHODS： Patients who are diagnosed with fungal corneal ulcer and treated with layer corneal transplantation were in control group. Those with fungal corneal ulcer that treated with lamellar keratoplasty in experimental group, as well as they were injected with 0. lmL fluconazole （0. 05mL 2g/L fluconazole ＋ 0.05mL normal saline） into the anterior chamber for three times during operation, at the 3rd day and 10th day after operations. RESULTS. The recurrence rate was 11% in control group, while no recurrence for experimental group in a 3- to 6- month follow up observation. CONCLUSION： The combination of anterior chamber injection into lamellar keratoplasty is an efficient approach to cure fungal corneal ulcer, and shows low recurrence rate.

关 键 词：板层角膜移植 前房注药 真菌性角膜溃疡 

分 类 号：R779.6[医药卫生—眼科]