影响LASEK乙醇浸润法制备角膜上皮瓣时间的相关因素  

Analysis of factors influencing preparation of corneal flap time in LASEK

作　　者：魏芬[1] 艾明[2] 许鸣[1] 肖秀兰[1] 

机构地区：[1]中国湖北省荆州市中心医院眼科,434020 [2]武汉大学人民医院眼科,中国湖北省武汉市430000

出　　处：《国际眼科杂志》2013年第10期2157-2159,共3页International Eye Science

摘　　要：目的：探讨影响LASEK角膜上皮瓣制作时间的相关因素。方法：回顾性分析选取2009-08/2012-08在我院行LASEK治疗的近视患者320例640眼,将患者按年龄分组,18～23岁、24～29岁、30～35岁、大于35岁4组（A,B,C,D）,每组按是否配戴隐形眼镜超过3mo,分为2个亚组（I,II）,统计每组的平均制瓣时间。结果：大部分患者于术后2～4h后有异物感、疼痛等眼部刺激症状。术后7d左右角膜上皮基本愈合,20d左右视力基本恢复到最佳。术后6mo平均裸眼视力1.23±0.15。制瓣时间11～30（平均18±3.5）s,随着年龄的增加,制瓣时间明显延长,配戴隐形眼镜的时间大于3mo的患者,制瓣时间也明显延长,同年龄段2个亚组（Ⅰ,Ⅱ）作统计学处理,差异有显著性（P〈0.05）。同年龄段男、女患者制瓣时间差异不明显（P〉0.05）。结论：随着年龄的增加,制瓣时间明显延长。长期配戴角膜接触镜是影响上皮瓣制作成功的重要因素,配戴隐形眼镜的时间大于3mo的患者,制瓣时间也明显延长。AIM： To explore the factors affecting on the making time of LASEK corneal flap. METHODS：A retrospective analysis from August 2009 to August 2012 in our hospital in 320 cases treated by LASEK in myopic patients （640 eyes）, the patients were grouped according to age, 18-23 years, 24-29 years, 30- 35 years, and greater than 35 year were divided into 4 groups （A, B, C, D）, each group according to whether wearing contact lenses for more than 3 months, divided into 2 subgroups （I, II）, the average flap preparation time statistics for each group. RESULTS： Most of the patients in postoperative 2-4h after a foreign body sensation, presented ocular pain. Corneal epithelium was basically healed after about 7days. Visual acuity recovered to the best after 20d. After 6 months, the average visual acuity was 1.23±0.15. Flap preparation time 11 - 30s, average 18± 3. 5s. With the increase of age, flap preparation time was significantlyprolonged. For those wearing contact lens over 3 months, flap preparation time was significantly longer. There was significant difference （P〈0.05） after analyzing the same age as 2 subgroups （I, II）. Flap preparation time in male and female patients with the same age had no significantly difference （P〉0.05）. CONCLUSION： With the increase of age, flap preparation time is significantly prolonged. Long-term wear contact lens is the important factor in the success of production. For those wearing contact lens over 3 months, flap preparation time was significantly longer.

关 键 词：LASEK 角膜上皮瓣 时间 相关因素 

分 类 号：R779.63[医药卫生—眼科]