25例代谢性脑病临床分析  

Clinical Analysis of 25 Patients with Metabolic Encephalopathy

作　　者：季苏琼[1] 熊永洁[1] 张萍[1] 毛志娟[1] 逯青丽[2] 薛峥[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院神经内科,武汉430030 [2]华中科技大学同济医学院附属同济医院综合科,武汉430030

出　　处：《神经损伤与功能重建》2013年第5期364-366,共3页Neural Injury and Functional Reconstruction

摘　　要：目的：探讨25例代谢性脑病患者的临床特征。方法：回顾性分析我科2003年1月～2013年1月确诊为代谢性脑病的住院患者25例。结果：25例患者中，发病年龄无一定规律性，血糖异常及电解质异常者各6例，肝功能异常3例，肾功能异常4例；5例行血气分析，均有异常；7例患者行脑电图检查，6例阳性（85％）；7例行头部CT，阳性2例（28．6％），13例行头部MRI检查，阳性10例（76．9％）。结论：代谢性脑病病因多样，发病机制复杂，诊断标准不明确，但脑电图的诊断具有积极意义，MRI检查缺乏特异性，治疗以支持对症治疗为主，早期诊断，早期治疗预后可。Objective： To study the clinical characteristics of patients with metabolic encephalopathy. Methods： The clinical data of 25 patients with metabolic encephalopathy diagnosed and treated in our hospital from Jan. 2003 to Jan. 2013 were studied retrospectively. Results： In the 25 cases, their onset ages varied. Blood glucose and/or electrolytes were abnormal in 6 cases. Liver dysfimction and/or renal dysfunction was found in 7 cases, abnormalities of blood gas analysis were seen in 5 cases. Seven patients revealed EEG abnormalities, 2 cases had abnormal changes on CT scan, and 10 cases were observed to have pathological changes on MRI. Conclu- sion： Diagnostic criteria for metabolic encephalopathy were multiple and complex. Since pathogenesis varies form case to case, there is no definite diagnostic criteria. Seeking for etiology in each case is the first priority. The management of acute metabolic encephalopathy is basically symptomatic. Early diagnosis and prompt treatment will yield satisfactory prognosis.

关 键 词：代谢性脑病 临床特征 回顾性分析 

分 类 号：R741[医药卫生—神经病学与精神病学] R742[医药卫生—临床医学]