双模式超声光散射乳腺成像系统在乳腺疾病良恶性鉴别中的临床应用价值  

Clinical application value of modality ultrasound with diffused optical imaging system in distinguishing benign/malignant lesions for mammary gland disease

作　　者：喻灿球[1] 唐中华[1] 周恩相[1] 谷社营 孙卫红[3] 胡平成[4] 

机构地区：[1]中南大学湘雅二医院,湖南长沙410011 [2]中国新奥博为技术有限公司 [3]山东昌邑市人民医院 [4]中南大学公共卫生学院

出　　处：《中国现代医学杂志》2013年第22期74-77,共4页China Journal of Modern Medicine

摘　　要：目的评价双模式超声光散射乳腺成像系统(OPTIMUS)在乳腺疾病诊断中的临床应用价值。方法应用OPTIMUS随机检测18 726例次患者。根据BI-RADS分级标准,系统对乳腺病变进行良恶性分级,并与术后病理对照分析。结果 1 948例被检出乳腺肿块,经手术证实良性1 385例,恶性563例。OPTIMUS的诊断吻合率93.6%(1 823/1 948),敏感性88.6%(499/563),特异性95.6%(1 324/1 385)。结论 OPTIMUS可用于乳腺肿块良性鉴别,能有效提高乳腺癌的检出率,减少不必要的活检。[ Objective ] To evaluate the clinical application values of dual modality ultrasound with diffuse optical imaging system in distinguishing benign/malignant lesions for mammary gland disease. [Method ] OPTIMUS were operated randomly on 18 726 patients with mammary gland disease. According to the BI-RADS, the benign/malig- nant lesions were automatically assessed on the equipment, and the sensitivity, specificity and overall accuracy were determined by surgical pathology as gold standard. [Results] There were 1 385 benign and 563 malignant lesions. The sensitivity, specificity and accuracy of OPTIMUS were 88.6%（499/563）,95.6%（1324/1385）, 93.6% （1 823/1 948）, respectively. [ Conclusion ] OPTIMUS could be used as an assistant diagnostic tool for differentiating benign and malignant lesions and avoiding unnecessary biopsy as possible.

关 键 词：超声光散射成像 乳腺疾病 

分 类 号：R737.9[医药卫生—肿瘤]