支气管动脉介入治疗中晚期中央型肺癌的疗效分析  

Bronchial arterial interventional treatment of late stage central lung cancer

作　　者：张守民 王国兴 孟庆东 陈友国 郝连军[2] 

机构地区：[1]251700山东省滨州市结核病防治院放射科 [2]050071石家庄,河北省血液中心检验科

出　　处：《国际呼吸杂志》2013年第18期1371-1373,共3页International Journal of Respiration

摘　　要：目的 探讨支气管动脉介入治疗中晚期中央型肺癌的临床疗效.方法 39例患者中采取支气管动脉化疗加栓塞25例,单纯支气管动脉灌注化疗14例；其中肿瘤为富血管型28例,乏血管型11例,全部病例术后随访6～12个月.结果 每组患者有效例数及有效率（完全缓解＋部分缓解）分别为：支气管动脉化疗加栓塞21例（84.00％）,单纯支气管动脉灌注化疗7例（50.00％）；富血管型23例（82.14％）,乏血管型5例（45.45％）.结果显示,支气管动脉化疗加栓塞疗效明显优于单纯支气管动脉灌注化疗（P＜0.05）；富血管型与乏血管型之间疗效比较差异有统计学意义（P＜0.05）.结论 支气管动脉化疗加栓塞已成为治疗中晚期中央型肺癌的有效方法之一.Objective To explore the clinical efficacy of central bronchial artery interventional treatment of advanced lung cancer. Methods In 39 patients, 25 cases received bronchial arterial chemotherapy and embolization and 14 cases received simple bronchial artery infusion chemotherapy. The tumor was hypervascular in 28 cases and 11 cases were lack of blood vessels. All patients were followed up for 6 to 12 months. Results The number of effective cases and efficient rate （complete response＋partial response） were： 21 cases （84.00%） in bronchial arterial chemotherapy and embolization, seven cases （50.00%） in simple bronchial arterial infusion chemotherapy, 23 cases （82.14%） in rich blood vessels, five cases （45.45%） in lack of blood vessels. The results showed that efficiency of bronchial arterial chemotherapy and embolization was better than that of simple bronchial artery infusion chemotherapy （ P〈0.05） ,there was significant difference in efficiency between rich vascular and lack of vascular （ P〈0.05）. Conclusions Bronchial arterial chemotherapy and embolization has become one of the effective method in treatment of advanced central type lung cancer.

关 键 词：肺癌 介入治疗 支气管动脉 

分 类 号：R734.2[医药卫生—肿瘤]