原发性肺黑色素瘤1例报道并文献复习  

A case of primary malignant melanoma of lung and literature review

作　　者：贾建军[1] 刘瑞娟[1] 韩丽萍[1] 

机构地区：[1]272000济宁市第一人民医院呼吸内科

出　　处：《国际呼吸杂志》2013年第18期1380-1382,共3页International Journal of Respiration

摘　　要：目的 分析原发性肺黑色素瘤（PMML）的流行病学及临床、病理特点,提高临床医师对PMML的诊断水平.方法 报道了济宁市第一人民医院呼吸科1例经病理确诊的PMML,并对其病理特点及32例PMML患者的治疗进行回顾分析.结果 患者,男,22岁,主因“反复咯血8个月,加重3d”于2011年3月31日在我院呼吸科住院治疗.肺CT是多发结节灶,后行胸腔镜肺活检病理示黑色素瘤.迄今为止,国外诊断PMML 32例,国内报道22例,主要症状为咯血,咳嗽.影像学为孤立性病灶多见.结论 本例肺内多发结节的PMML患者在国内外都是首例报道.手术是目前最好的方法,晚期可以给予放化疗.Objective To investigate the pathohistological morphology and clinical features of primary malignant melanoma of the lung （PMML） and improve the diagosis level of clinician. Methods A rare case of PMML in Jining First People~ s Hospital was reported and the pathohistologieal morphology and therapy of 32 cases of PMML were retrospectively analyzed. Results A 22 year old male had comlainted hemoptysis for eight months and aggravation for three days. Computed tomography showed many nodles in the lung. Pathohistology showed primary malignant melanoma through thoraeoscope. 32 cases of PMML had been previously reported in foreign literatures and 22 in abroad literatures,the symptom was mostly hemoptysis and cough. Computed tomography showed isolated bolus. Conclusions The case of PMML with many nodles in the lung is reported firstiy in abroad and domestic. Surgical completed resection is th e first option of therapeutic strategy. Chemotherapy and radiotherapy can be selected in the advanced stage.

关 键 词：黑色素瘤 肺 CT 

分 类 号：R734.2[医药卫生—肿瘤]