先天性唇腭裂528例临床分析  

Clinical and Statistical Analysis of 528 Patients with Cleft Lip and Palate

作　　者：王道和[1] 陈阳[2] 顾建英[1] 

机构地区：[1]复旦大学附属中山医院整形外科,上海200032 [2]上海交通大学医学院附属第九人民医院口腔颌面外科,上海200011

出　　处：《中国临床医学》2013年第3期357-359,共3页Chinese Journal of Clinical Medicine

基　　金：国家自然科学基金资助项目(编号:81070813)

摘　　要：目的:了解近年来在上海地区就诊的先天性唇腭裂患者的现状。方法:对上海交通大学医学院唇腭裂治疗研究中心2006年6月—2007年11月收治的528例先天性唇腭裂与面裂患者的临床资料进行分类整理,并进行回顾性统计分析。结果:528例患者中,男性313例,女性215例,男女比1.46∶1;本地患者83例,非本地患者445例;手术时年龄2个月～36岁,平均年龄6.95岁;术后住院时间1～15 d,平均住院时间5.54 d;伴发畸形0～3种,平均伴发畸形数0.44种;构成比:唇裂197例(37.31%)、腭裂217例(41.10%)、牙槽突裂48例(9.10%)、面横裂9例(1.70%)、腭咽闭合不全35例(6.63%)、腭心面综合征19例(3.60%)、Robin序列征5例(0.95%);各型的左右侧之比为2.10∶1。结论:近年来,上海地区出现腭裂患者多于唇裂患者的趋势,可能与孕妇产检和基层医院唇腭裂手术普及有关;腭裂手术后处置方法的改变,大大缩短了患者的住院时间。Objective：To investigate the status of patients with cleft lip and palate treated in a hospital of Shanghai City in recent years.Methods：The clinical datum of 528 cases of cleft lip and palate hospitalized in Therapy and Research Center of Cleft Lip and Palate of Shanghai Jiaotong University School of Medicine from Jun 2006 to Nov 2007 were collected,classified and analyzed statistically.Results： In 528 cases,there were 313 male cases and 215 female cases（male∶femail=1.46∶1）.The number of Shanghai and non-Shanghai cases were 83 and 445.The operating age varied from 2 months old to 36 years old with an average of 6.95 years old.The postoperation-hospital-stay varied from 1 to 15 days with an average of 5.54 days.The numbers of malformations which hadn＇t been treated varied from 0 to 3,and the average value was 0.44.The cleft morphology was classified as follows：lip cleft in 197 cases（37.31 %）,palate cleft in 217 cases（41.10 %）,alveolar cleft in 48 cases（9.10 %）,transverse facial cleft in 9 cases（1.70 %）,velopharyngeal incompetence in 35 cases（6.63 %）,velo-cardio-facial syndrome（VCFS） in 19 cases（3.60 %）,Robin sequence syndrome in 5 cases（0.95 %）.In all the classifications,left were more than right（left∶right=2.10∶1）.Conclusions： Cleft lip and palate are common malformations of oral and maxillofacial regions.There is a tendency of more cleft palate than cleft lip in recent years,which may due to the popularization of prenatal examination and cleft palate operation in primary hospital.

关 键 词：唇腭裂 临床资料 统计分析 治疗特点 

分 类 号：R782.2[医药卫生—口腔医学]