喀什261例维吾尔族孕妇膳食营养与不同孕期血浆同型半胱氨酸关系研究  

Study on the dietary nutrition and the relationship between plasma homocysteine in the different pregnancy periods among 261 cases of Uighur pregnant women from Kashi

作　　者：袁帅[1] 吐尔逊江·买买提明[1] 王明霞[1] 王晓军 王艳萍[3] 孙春梅[1] 

机构地区：[1]新疆医科大学公共卫生学院营养与食品卫生学教研室,新疆乌鲁木齐830011 [2]乌鲁木齐市妇幼保健医院/自治区妇幼保健培训中心 [3].新疆医科大学第二附属医院

出　　处：《现代预防医学》2013年第19期3589-3591,3596,共4页Modern Preventive Medicine

基　　金：教育部留学回国人员基金,教育部(教外司留[2009]1001号)

摘　　要：目的通过调查了解维吾尔族孕妇不同孕期血浆同型半胱氨酸(Hcy)水平及其变化规律,为深入研究孕妇营养与健康状况提供依据。方法以261例维吾尔族孕妇为调查对象,采用连续3 d 24 h膳食回顾法调查孕妇膳食营养素摄入状况;采用酶免疫检测法测定孕妇不同孕期血浆同型半胱氨酸水平。结果被调查维吾尔族孕妇的每日摄入的营养素中,碘、钙、铁、锌、维生素B1、维生素B2、维生素C的每日摄入量分别为105.37μg(占52.69%)、585.37mg(占58.53%)、27.92 mg(占79.77%)、12.54 mg(占76%)、1.19 mg(占73.10%)、1.15 mg(占67.60%)、53.60mg(占41.42%),维生素B12、叶酸的每日摄入量分别为1.33 mg(占51.20%)、123.65μg(占23.95%),其余的营养素摄入量均达到推荐供给量标准;不同孕期血浆同型半胱氨酸平均水平(16.86±4.92)μmol/L;孕早期(16.89±4.83)μmol/L和孕中晚期(16.83±5.01)μmol/L血浆同型半胱氨酸水平比较以及高同型半胱氨酸血症(HHcys)检出率比较,差异均无统计学意义(P﹥0.05)。结论被调查的维吾尔族孕妇膳食结构不合理,其中能量、蛋白质、磷、钠、硒、维生素A、烟酸摄入量偏高,钙、碘、铁、锌、维生素B1、维生素B2、维生素C不足,尤其是与Hcy代谢相关的维生素B12和叶酸的摄入量严重不足。各孕期血浆同型半胱氨酸水平均偏高。OBJECTIVE To investigate plasma homocysteine in the different pregnancy periods and variations of Uighur pregnant women, to provide a basis for further study on nutritional and health status of pregnant women. METHODS 261 cases of Uighur pregnant women were surveyed. Used the method of 3 consecutive days of 24-hour dietary recalls to survey the dietary intake status of pregnant women ; used the enzyme immunoassay method for the determination of plasma homocysteine of pregnant women during different pregnancy periods. RESULTS Among Uighur pregnant woman＇s daily nutrients investigat- ed, the daily intake of iodine, calcium, iron, zinc, vitamin B1, vitamin B2, vitamin C was 105.37μg （52.69%） , 585.37mg （58.53%）, 27.92mg （79.77%） , 12.54mg （76%） , 1.19mg （73.10%） , 1.15rag （67.60%） and 53.60mg （41.42%） respectively, the daily intake of Vitamin B12, folio acid was 1.33mg （51.20%）, 123.65ug （23.95%） respectively, the intakes of the rest nutrients all reached RDA; the average plasma homocysteine of different stages of gestation was （ 16.86 ±4.92） μmol/L; there was no difference statistically between the plasma homocysteine of early pregnancy （ 16.89 ± 4.83） μmol/L and that of progesterone in the late （16.83 ± 5.01） μmol/L （P 〉 0.05）, and the same to the detection rate of homocysteine viremia of them. CONCLUSION The dietary structure of Uighur pregnant women surveyed is irrational, includ- ing the higher intake of energy, protein, phosphorus, sodium, selenium, vitamin A, niacin, but the insufficient intake of calcium, iodine, iron, zinc, vitamin Bj, vitamin B2, vitamin C, especially serious shortage of vitamin B12 and folio acid associated with the homocysteine. The plasma homocysteine levels of each pregnancy period are all higher.

关 键 词：维吾尔族 孕妇 同型半胱氨酸 

分 类 号：R153.1[医药卫生—营养与食品卫生学]