1例多发性骨髓瘤治疗期间并发垂体危象  

Pituitary crisis in a multiple myeloma patient during treatment

作　　者：徐笑笑[1] 马中书[2] 于泳[1] 张连郁[3] 刘佩芳[4] 张鹏宇[5] 房淑霞[6] 张翼鷟[1] 

机构地区：[1]天津医科大学肿瘤医院血液科,国家肿瘤临床医学研究中心,天津市肿瘤防治重点实验室,天津市300060 [2]天津医科大学总医院内分泌科 [3]天津医科大学肿瘤医院病理科 [4]天津医科大学肿瘤医院放射科 [5]天津医科大学肿瘤医院检验科 [6]天津医科大学总医院消化内科

出　　处：《中国肿瘤临床》2013年第18期1130-1133,共4页Chinese Journal of Clinical Oncology

摘　　要：多发性骨髓瘤(myltiple myeloma,MM)是一种老年病,治疗原则以化疗为主。然而化学治疗相关的不良反应与希恩综合征的临床表现相似,对于无明确产后出血史的老年患者,往往容易造成误诊、漏诊。因此,老年多产的女性,在化疗期间出现顽固性低钠血症及消化道反应时,应考虑希恩综合征的可能,早期明确诊断,及时给予个体化治疗。Multiple myeloma is common in the older population and is treated mainly with chemotherapy. However, chemotherapy-related side effects imitate the clinical manifestations of Sheehan＇s syndrome, which leads to misdiagnosis and missed diagnosis, particularly for older patients without a clear history of postpartum hemorrhage. Therefore, when older women with malignant myelomas show refractory hyponatremia and gastrointestinal disorders while under chemotherapy, a diagnosis of Sheehan＇s syndrome should be considered. The early detection of the disorder will guarantee timely individualized treatment.

关 键 词：多发性骨髓瘤 希恩综合征个体化治疗 多学科协作 

分 类 号：R733.3[医药卫生—肿瘤]